Objective: to describe the experience and preliminary results of the Arbovirus Death Investigation Committee in Ceará, Brazil, in 2017.
Methods: the Committee investigates and discusses all suspected cases of arbovirus deaths reported by the epidemiological surveillance service.
Results: a total of 443 suspected arbovirus deaths were reported, 220 (49.7%) of which were confirmed; of these, 88.2% were from chikungunya and 11.8% from dengue; the median age of chikungunya deaths was higher when compared to dengue (77 versus 56 years) and the time until death was also longer when compared to dengue (38 versus 12 days); median time for case closure was 54.5 days; in 2017, Ceará confirmed 80.4% of Brazilian chikungunya deaths.
Conclusion: the investigation of deaths showed that CHIK viruses were responsible for the majority of arboviral deaths in the state of Ceará, in 2017.
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http://dx.doi.org/10.5123/S1679-49742019000300011 | DOI Listing |
Front Cell Infect Microbiol
December 2024
Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, United States.
Infectious diseases are the leading cause of death in infants and children under 5 years of age. exposure to viruses can lead to spontaneous abortion, preterm birth, congenital abnormalities or other developmental defects, often resulting in lifelong health sequalae. The underlying biological mechanisms are difficult to study in humans due to ethical concerns and limited sample access.
View Article and Find Full Text PDFArq Neuropsiquiatr
December 2024
Universidade Federal do Estado do Rio de Janeiro, Escola de Medicina e Cirurgia, Rio de Janeiro RJ, Brazil.
Dengue is the main urban arbovirus in the Americas. The disease manifests in a varied spectrum: from asymptomatic cases to those with neurological involvement, which is considered a severe form of the disease. Its annual reemergence represents a serious public health problem.
View Article and Find Full Text PDFPathogens
November 2024
Laboratorio Analisi Chimico Cliniche e Microbiologia, Presidio Ospedaliero Duilio Casula, Azienda Ospedaliero Universitaria di Cagliari, Monserrato, 09042 Cagliari, Italy.
Japanese encephalitis (JE) is preventable using the affordable, effective, and safe live attenuated SA 14-14-2 JE vaccine (CD-JEV). We used a Markov model to evaluate the cost-effectiveness of 1 dose of CD-JEV compared with no vaccination in 3 vaccination strategies in Bangladesh: subnational campaign and routine immunization, subnational campaign and national routine immunization, and national routine immunization alone. For input parameters, we gathered information from a cost-of-illness study, medical literature, government documents, and expert opinions.
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