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http://dx.doi.org/10.1016/j.jdcr.2019.10.009 | DOI Listing |
Invest Ophthalmol Vis Sci
January 2025
Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Purpose: Ocular neovascularization is a major cause of blindness. Although fibroblast growth factor-2 (FGF2) has been implicated in the pathophysiology of angiogenesis, the underlying mechanisms remain incompletely understood. The purpose of this study was to investigate the role of FGF2 in retinal neovascularization and elucidate its underlying mechanisms.
View Article and Find Full Text PDFInt Ophthalmol
January 2025
Department of Ophthalmology, Xingtai People's Hospital, Xingtai, 054001, Hebei, China.
Background: Retinopathy of prematurity (ROP) is a major cause of childhood blindness worldwide, highlighted by retinal neovascularization. Ubiquitin is present throughout the retina. The deubiquitinating enzyme ubiquitin-specific protease 39 (USP39) has been reported to be involved in angiogenesis.
View Article and Find Full Text PDFActa Parasitol
January 2025
Cytokines and NO Synthases Team, LBCM, FSB, USTHB, BP 32 El Alia, Bab Ezzouar, Algiers, 16111, Algeria.
Purpose: Since extract of the laminated layer (LL) from E. granulosus showed immuno-modulatory effects in vitro and in vivo, we sought to determine its effect on the onset, development, and evolution of experimental auto-immune uveitis (EAU). The latter is a model of some human diseases with ocular inflammation that can cause blindness.
View Article and Find Full Text PDFTrop Med Infect Dis
December 2024
Centro Nacional de Epidemiología, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Background: Onchocerciasis, or river blindness, is one of the neglected tropical diseases (NTDs) that the WHO has set out to eliminate. To reach this elimination target, a number of challenges must be met, and the essential measures set out in the road map for NTDs 2021-2030 must be implemented. More than 99% of infected people live in 31 countries in sub-Saharan Africa.
View Article and Find Full Text PDFHealth Aff Sch
January 2025
Burton Blatt Institute, Syracuse University, Syracuse, NY 13244-2130, United States.
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