Congestive heart failure-related hospital deaths across the urban-rural continuum in the United States.

Prev Med Rep

Department of Health Policy and Management, School of Public Health, Texas A&M University, College Station, TX 77843-1266, USA.

Published: December 2019

Congestive heart failure (CHF) is a growing public health problem that affects nearly 6.5 million individuals nationwide. Access to quality outpatient care and disease management programs has been shown to improve disease treatment and prognosis. Rural populations face unique challenges in the availability and accessibility of quality cardiovascular care. In 2018, we conducted a pooled cross-sectional analysis of the Nationwide Inpatient Sample (NIS) for 2009-2014 to examine recent trends in CHF-related hospital deaths in the United States, highlighting urban-rural differences within each census region. We performed a multivariable logistic regression analysis to compare the odds of CHF-related hospital death by levels of rurality and within each census region. Most CHF-related hospital deaths occurred in the South and Midwest census regions and in large central metropolitan areas. Findings from census region stratified models revealed that non-core residents living within the West (OR 1.47, CI 1.26, 1.71), Midwest (OR 1.30, CI 1.17, 1.44), and South (OR = 1.21, 95% C.I. = 1.12-1.32) had a higher relative risk (but not higher absolute numbers) of experiencing death during a CHF-related hospitalization, compared to patients in large central metropolitan areas. Within each census region, there were also differences in odds of a CHF-related hospital death depending on patient sex, comorbidities, insurance type, median annual income, and year. As efforts to reduce rural health disparities in CHF morbidity continue, more work is needed to understand and test interventions to reduce the risk of death from CHF in noncore areas of the West, Midwest, and South.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883321PMC
http://dx.doi.org/10.1016/j.pmedr.2019.101007DOI Listing

Publication Analysis

Top Keywords

chf-related hospital
16
census region
16
hospital deaths
12
congestive heart
8
united states
8
odds chf-related
8
hospital death
8
large central
8
central metropolitan
8
metropolitan areas
8

Similar Publications

Exploring diagnostic biomarkers of type 2 cardio-renal syndrome based on secreted proteins and bioinformatics analysis.

Sci Rep

October 2024

The Affiliated Lihuili Hospital of Ningbo University, Health Science Center, Ningbo University, No.57, Xingning Road, Ningbo, 315040, Zhejiang Province, China.

Article Synopsis
  • Chronic heart failure (CHF) can lead to chronic kidney disease (CKD), known as type 2 cardio-renal syndrome (CRS2), but the exact mechanisms and early biomarkers for CKD are not well understood.
  • Researchers analyzed several expression datasets to identify key genes linked to CKD and secreted proteins related to CHF, uncovering 225 CKD genes and 316 CHF proteins, with four key gene subgroups involved in CRS2's pathology.
  • Machine learning methods highlighted three potential biomarkers (CD48, COL3A1, LOXL1) for CKD, forming a diagnostic model that exhibited strong predictive power and a significant correlation with kidney function metrics.
View Article and Find Full Text PDF

Background: Obesity increases risk of atrial fibrillation (AF) at least in part due to pro-inflammatory effects, but has been paradoxically associated with improved mortality. Although statins have pleiotropic anti-inflammatory properties, their interaction with obesity and clinical outcomes in AF is unknown. We explored the relationship between BMI, statin use, and all-cause mortality and AF/congestive heart failure (CHF)-related encounters, hypothesizing that statin exposure may be differentially associated with improved outcomes in overweight/obesity.

View Article and Find Full Text PDF

Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure.

Aging (Albany NY)

July 2024

Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.

Background: Chronic heart failure (CHF) impairs cognitive function, yet its effects on brain structure and underlying mechanisms remain elusive. This study aims to explore the mechanisms behind cognitive impairment.

Methods: CHF models in rats were induced by ligation of the left anterior descending coronary artery.

View Article and Find Full Text PDF

Background: Physical activity (PA) is essential and effective for chronic heart failure (CHF) patients. A greater understanding of the longitudinal change in PA and its influencing factors during the postdischarge transition period may help create interventions for improving PA. The aims of this study were (1) to compare the change in PA, (2) to examine the influencing factors of PA change, and (3) to verify the mediating pathways between influencing factors and PA during the postdischarge transition period in CHF patients.

View Article and Find Full Text PDF

The global rise of obesity and its association with cardiovascular risk factors (CVRF) have highlighted its connection to chronic heart failure (CHF). Paradoxically, obese CHF patients often experience better outcomes, a phenomenon known as the 'obesity paradox'. This study evaluated the 'obesity paradox' within a large cohort in Germany and explored how varying degrees of obesity affect HF outcome.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!