AI Article Synopsis
- Patients with end-stage renal disease undergoing hemodialysis have low fitness and quality of life, leading researchers to test whether high-intensity interval training (HIIT) could improve these outcomes compared to moderate-intensity continuous training (MICT).
- The study involved 20 patients divided into HIIT, MICT, and usual care groups, assessing session attendance, safety, and changes in fitness (peak oxygen uptake) and quality of life through various tests and questionnaires.
- Results showed that HIIT was feasible and safe, with some patients experiencing notable improvements in cardiorespiratory fitness, but larger studies are needed to fully understand its effectiveness in this population.
Article Abstract
Objectives: Patients with end-stage renal disease (ESRD) undergoing haemodialysis (HD) have significantly reduced cardiorespiratory fitness and health-related quality of life (HRQoL). Our hypothesis was that high-intensity interval training (HIIT) is a feasible and safe form of exercise during HD and that HIIT would elicit greater change in cardiorespiratory fitness and HRQoL compared with moderate-intensity continuous training (MICT).
Methods: Twenty patients were randomised to either HIIT (n=6), MICT (n=8) (two times a week within 22 weeks) or usual care (n=6). Feasibility was assessed by session attendance and adherence to exercise intensity. Safety was assessed by adverse event reporting. Efficacy was determined from change in peak oxygen uptake (VO), 6 min walk distance and a HRQoL questionnaire (the COOP-WONCA chart).
Results: Eleven patients (55%) completed premeasurements and postmeasurements. The main reason for drop-out was due to kidney transplant during follow-up. The patients completed the same number of sessions in each group and adhered to the target heart rates after habituation. There were no adverse events. In the HIIT group, two of the three patients increased VO by 46% and 53%, respectively. Three of the five patients in the MICT group increased their VO by 6%, 18% and 36%, respectively.
Conclusions: This pilot study demonstrated that HIIT is a feasible and safe exercise model for intradialytic exercise in patients undergoing HD. There might be a considerable potential of intradialytic HIIT in patients undergoing HD. Further studies with larger sample sizes are needed to determine if HIIT is an optimal approach in patients with ESRD undergoing HD.
Trial Registration Number: NCT01728415.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863672 | PMC |
| http://dx.doi.org/10.1136/bmjsem-2019-000617 | DOI Listing |
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