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| http://dx.doi.org/10.3389/fpsyg.2019.02602 | DOI Listing |
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Omics Biology in Diagnosis of Diseases: Towards Empowering Genomic Medicine from an Evolutionary Perspective.
Life (Basel)
December 2024
MIBS Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland.
In this section, we reintroduce the original aims and scope of the Special Issue entitled "Omics Biology in Diagnosis of Diseases: Advances in Bioinformatics and Data Analyses", enabling readers to find an appropriate framing for the remainder of the present closing editorial [...
View Article and Find Full Text PDFHow does age impact understanding of epistemic adverbs in health communication?
Geriatr Nurs
January 2025
School of Psychology and Counselling, Queensland University of Technology, Brisbane, Australia.
Objective: Not much is known about how one's understanding of words may differ with age. Here we explore how epistemic adverbs - as used in health communication to indicate degrees of uncertainty and risk - are understood by older and younger monolingual speakers of Australian English.
Methods: We used an online dissimilarity rating task with sentence pairs presented as first and second doctor opinions which differed only with respect to the embedded epistemic adverbs (e.
Lymph node assessment at the time of robotic hysterectomy for endometrial intraepithelial neoplasia: A cost-effectiveness analysis.
Gynecol Oncol
January 2025
Division of Gynecologic Oncology, St. Luke's University Health Network, Bethlehem, PA, United States of America.
Objective: We sought to determine the cost-effectiveness (CE) of lymph node dissection (LND) at the time of hysterectomy for endometrial intraepithelial neoplasia (EIN).
Methods: A decision analytic model was created to evaluate the strategies of routine full LND, sentinel lymph node dissection (SNLD), SNLD without advancing to full LND in the event of non-mapping, and full LND based on Mayo Criteria, versus no LND. Patients in the no LND group and those in the SLND group without advancement to full LND in the event of non-mapping who were found to have EC on final pathology and suspicious post-operative imaging underwent full LND.
Chronic nicotine exposure induces molecular and transcriptomic endophenotypes associated with mood and anxiety disorders in a cerebral organoid neurodevelopmental model.
Front Pharmacol
December 2024
Addiction Research Group, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
Introduction: Prenatal nicotine exposure (PNE) from maternal smoking disrupts regulatory processes vital to fetal development. These changes result in long-term behavioral impairments, including mood and anxiety disorders, that manifest later in life. However, the relationship underlying PNE, and the underpinnings of mood and anxiety molecular and transcriptomic phenotypes remains elusive.
View Article and Find Full Text PDFMacro-level socioeconomic factors and mental health in midlife and older adults in China: a multilevel analysis.
Front Public Health
January 2025
Guangzhou Development Academy, Guangzhou University, Guangzhou, China.
Objective: This study explores the associations between four macro-level factors-Economic Development (ED), Economic Inequality (EI), Governmental Willingness and capacities to invest in Public Health (GWPH) and Public Health-Related Infrastructures (PHRI)-and three mental health indicators: depressive symptoms, cognitive function and life satisfaction, among middle-aged and older adults in China.
Materials And Methods: We obtained individual-level data from the Harmonised China Health and Retirement Longitudinal Survey (H-CHARLS) 2018 and acquired our provincial-level data from the Chinese Statistical Yearbook. Two-level linear mixed models are used to examine the associations.
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