Prominin-2 Suppresses Ferroptosis Sensitivity.

Dev Cell

Division of Nephrology, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany; Biotechnology Center, Technische Universität Dresden, 01307 Dresden, Germany. Electronic address:

Published: December 2019

Ferroptosis causes clinically relevant amounts of necrosis during the course of heart attacks and acute kidney injury. However, ferroptosis is still a very young research field. In this issue of Developmental Cell, Brown et al. describe the pentaspan membrane glycoprotein prominin-2 as a novel endogenous ferroptosis inhibitor.

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http://dx.doi.org/10.1016/j.devcel.2019.11.004DOI Listing

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