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Balancing Act: Cell Polarity and Shape Compete to Ensure Robust Development. | LitMetric
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Balancing Act: Cell Polarity and Shape Compete to Ensure Robust Development.

Lyndsay M Murrow Zev J Gartner

Dev Cell

Department of Pharmaceutical Chemistry and Center for Cellular Construction, University of California, San Francisco, San Francisco, CA 94158, USA; Chan Zuckerberg Biohub, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

Published: December 2019

In this issue of Developmental Cell, Niwayama et al. (2019) describe a model in which cell polarity and cell shape compete to determine the orientation of cell division in the pre-implantation mouse embryo. This model explains how simple cell-intrinsic rules lead to robust tissue-level morphogenesis and lineage segregation.

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 Source
http://dx.doi.org/10.1016/j.devcel.2019.11.008DOI Listing

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