Neonate gut colonization: The rise of a social brain.

Neurogastroenterol Motil

Division of Gastroenterology, Department of Internal Medicine, University Hospital of Patras, Rio, Greece.

Published: May 2020

Background: The human gut microbiota constitutes an integral part of human physiology, playing an important role in maintaining health, and compositional or functional changes in intestinal microbiota may be associated with the emergence of several chronic diseases. Animal and human studies have shown that there is a dynamic cross-talk between intestinal microorganisms and brain networks which has an impact on neurodevelopment and may be extremely critical in shaping human social behavior.

Purpose: The aim of the current review is to appraise and present in a concise manner all findings linking the evolution of neonate and infant gut colonization with early social development and to formulate scientifically informed hypotheses which could guide future research on this field.

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Source
http://dx.doi.org/10.1111/nmo.13767DOI Listing

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