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Assessment by miRNA microarray of an autologous cancer antigen-pulsed adoptive immune ensemble cell therapy (AC-ACT) approach; demonstrated induction of anti-oncogenic and anti-PD-L1 miRNAs. | LitMetric
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Assessment by miRNA microarray of an autologous cancer antigen-pulsed adoptive immune ensemble cell therapy (AC-ACT) approach; demonstrated induction of anti-oncogenic and anti-PD-L1 miRNAs.

Masanobu Chinami Kaoru Iwabuchi Yoshiteru Muto Yasuhiko Uchida Ryu Arita Rana A Shuraim Chaker N Adra

Clin Case Rep

BFSR Institute Fukuoka Japan.

Published: November 2019

A 60-year-old woman with stage IV rectal cancer received adoptive cell therapy with autologous cancer antigen (AC-ACT) causing induction of anti-oncogenic and anti-PD-L1 miRNAs as assessed by miRNA microarray. More than 1 year after AC-ACT, metastases have been arrested, and the patient reports good quality of life.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878052PMC
http://dx.doi.org/10.1002/ccr3.2343DOI Listing

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