The effectiveness of the psychotherapeutic treatment of posttraumatic stress disorder is evidence-based and generally considered proven. However, the effectiveness of multimodal, group-based day clinic treatment programs has rarely been investigated. Moreover, there is no consensus in the literature concerning the question whether psychotherapeutic approaches for trauma-related disorders are also applicable for patients with complex PTSD (cPTSD). The aim of the study was to evaluate our multimodal group-based treatment program regarding a change of psychiatric burden, a change of protective factors, and possible differences in therapy outcome for patients with or without cPTSD. The group-based treatment for patients with trauma-related disorders was examined in 66 patients who filled out the following questionnaires in the first and in the last week of treatment: Essen Trauma Inventory (ETI), Screening for complex PTSD (SkPTBS), Patient Health Questionnaire-somatization module (PHQ-15), Beck Depression Inventory-Revised (BDI-II), Posttraumatic Growth Inventory (PTGI), and Questionnaire on social support (F-SozU). The treatment was shown to significantly reduce depressive symptoms (p < 0.001, d = -0.536) and increase posttraumatic growth (New Possibilities: p = 0.004, d = 0.405; Personal Strength: p = 0.005, d = 0.414). For patients with cPTSD, depressive (p = 0.010, d = -0.63) as well as cPTSD symptoms (p = 0.020, d = -0.796) were significantly reduced; perceived social support was increased after day clinic treatment (p = 0.003, d = 0.61). Contrary to our expectations, somatoform symptoms were increased after therapy. The present work expands previous research by demonstrating that multimodal group-based, day clinic treatment is effective in the treatment of trauma-related disorders, also in their complex form.
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http://dx.doi.org/10.3389/fpsyt.2019.00800 | DOI Listing |
J Interpers Violence
December 2024
Department of Psychological Sciences, University of Missouri-St. Louis, USA.
On August 9, 2014, Michael Brown was shot and killed by police officer Darren Wilson in Ferguson Missouri, sparking protests and civil unrest. Three studies have yielded inconsistent findings regarding the presence of posttraumatic stress symptoms (PTSSs) in the aftermath of the unrest in Ferguson. Additional work is needed to understand how exposure to community-level stressors may correspond with trauma-related outcomes, as well as accounting for knowledge of, and engagement in the events.
View Article and Find Full Text PDFPsychiatr Danub
December 2024
Department of Psychiatry, Faculty of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
The present study aims to explore the self-reported traumatic stress symptoms related to the impact of the COVID-19 outbreak and to investigate associations among trauma-related stress symptoms, demographic, work-related, and clinical characteristics in a sample of professionals drawn from psychiatric services in Greece. The following online questionnaires were used in this study. An I.
View Article and Find Full Text PDFBehav Pharmacol
December 2024
Department of Pharmacology, Center of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Traumatic stress exposure increases noradrenaline (NA) release, which contributes to anxiety and impaired risk-appraisal. Guanfacine, a selective alpha-2A adrenergic receptor agonist, has been used to treat stress-related disorders characterised by impaired prefrontal cortex function. By acting on both presynaptic inhibitory autoreceptors and postsynaptic heteroreceptors, guanfacine attenuates stress reactivity and enhances cognition.
View Article and Find Full Text PDFInjury
December 2024
College of Nursing, Medical University of South Carolina, Charleston, SC, USA.
Background: The American College of Surgeons now requires mental health screening and follow up for hospitalized patients in trauma centers. National estimates indicate that 20-40 % of these patients will develop posttraumatic stress disorder (PTSD) and/or depression within one year post-injury. Research has identified brief bedside screens that predict PTSD and depression post-discharge, such as the Injured Trauma Survivor Screen and Peritraumatic Distress Inventory.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
December 2024
Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA 02478.
Genes involved in regulating the hypothalamic-pituitary-adrenal (HPA) axis, including the glucocorticoid receptor (GR), are linked to various stress-related psychopathologies including bipolar disorder as well as other mood and trauma-related disorders. The protein product of the cell cycle gene, is a GR interaction partner in peripheral cells. However, the precise roles of SKA2 in stress and GR signaling in the brain, specifically in nonreplicating postmitotic neurons, and its involvement in HPA axis regulation remain unclear.
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