AI Article Synopsis
- - Masson et al. (2019) explored how responses to low oxygen (hypoxia) are influenced by the degradation of specific proteins in different kingdoms like animals and plants.
- - They discovered a mammalian version of an oxygen-sensing pathway that had only been seen in plants before, highlighting a cross-kingdom similarity.
- - This research, along with other recent studies, offers fresh perspectives on how eukaryotic organisms detect and respond to oxygen levels.
Article Abstract
Responses to hypoxia are regulated by oxygen-dependent degradation of kingdom-specific proteins in animals and plants. Masson et al. (2019) identified and characterized the mammalian counterpart of an oxygen-sensing pathway previously only observed in plants. Alongside other recent findings identifying novel oxygen sensors, this provides new insights into oxygen-sensing origins and mechanisms in eukaryotes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cell.2019.10.043 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Risky behavior in virtual reality: The roles of personality, environment, and physiology.
PLoS One
January 2025
Faculty of Philosophy, Department of Psychology, University of Novi Sad, Novi Sad, Serbia.
Virtual reality (VR) provides a unique opportunity to simulate various environments, enabling the observation of human behavior in a manner that closely resembles real-world scenarios. This study aimed to explore the effects of anticipating reward or punishment, personality traits, and physiological arousal on risky decision-making within a VR context. A custom VR game was developed to simulate real-life experiences.
View Article and Find Full Text PDFTowards constructing a generalized structural 3D breathing human lung model based on experimental volumes, pressures, and strains.
PLoS Comput Biol
January 2025
Department of Mechanical Engineering, University of California Riverside, Riverside, California, United States of America.
Respiratory diseases represent a significant healthcare burden, as evidenced by the devastating impact of COVID-19. Biophysical models offer the possibility to anticipate system behavior and provide insights into physiological functions, advancements which are comparatively and notably nascent when it comes to pulmonary mechanics research. In this context, an Inverse Finite Element Analysis (IFEA) pipeline is developed to construct the first continuously ventilated three-dimensional structurally representative pulmonary model informed by both organ- and tissue-level breathing experiments from a cadaveric human lung.
View Article and Find Full Text PDFClinical Decision Support Using Speech Signal Analysis: Systematic Scoping Review of Neurological Disorders.
J Med Internet Res
January 2025
Knight Foundation of Computing & Information Sciences, Florida International University, Miami, FL, United States.
Background: Digital biomarkers are increasingly used in clinical decision support for various health conditions. Speech features as digital biomarkers can offer insights into underlying physiological processes due to the complexity of speech production. This process involves respiration, phonation, articulation, and resonance, all of which rely on specific motor systems for the preparation and execution of speech.
View Article and Find Full Text PDFGender Differences in the Association Between Anxiety and Interoceptive Insight.
Eur J Neurosci
January 2025
Translational Neuromodeling Unit, University of Zurich and ETH Zurich, Zurich, Switzerland.
Anxiety is one of the most common and debilitating mental health disorders, and is related to changes in interoception (perception of bodily states). While anxiety is more prevalent in women than men, gender differences in interoception-anxiety associations are often overlooked. Here, we examined gender-specific relationships between anxiety and interoception in the breathing domain, utilising multicentre data pooled from four study sites (N = 175; 51% women).
View Article and Find Full Text PDFGut microbiota are fundamental for healthy animal function, but the evidence that host function can be predicted from microbiota taxonomy remains equivocal, and natural populations remain understudied compared to laboratory animals. Paired analyses of covariation in microbiota and host parameters are powerful approaches to characterise host-microbiome relationships mechanistically, especially in wild populations of animals that are also lab models, enabling insight into the ecological basis of host function at molecular and cellular levels. The fruitfly is a preeminent model organism, amenable to field investigation by 'omic analyses.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!