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Solid-State Oxide-Ion Synaptic Transistor for Neuromorphic Computing.
Adv Mater
December 2024
Catalonia Institute for Energy Research (IREC), Jardins de les Dones de Negre 1, 2, Sant Adriá de Besós, Barcelona, 08930, Spain.
Neuromorphic hardware facilitates rapid and energy-efficient training and operation of neural network models for artificial intelligence. However, existing analog in-memory computing devices, like memristors, continue to face significant challenges that impede their commercialization. These challenges include high variability due to their stochastic nature.
View Article and Find Full Text PDFOne hundred years of success in antimicrobials: but what will the next 100 years bring?
Rev Sci Tech
December 2024
In the past 100 years, thanks to the discovery and development of antimicrobial therapies, human and veterinary medicine have made a leap forward in treating infectious diseases. However, resistance mechanisms quickly appeared and spread in all sectors - human, animal and environmental - throughout the world, thus jeopardising the progress made. Awareness has been raised only gradually but is now prominent at the global level, due in large part to the action of international organisations such as the World Organisation for Animal Health (WOAH), the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO), and antimicrobials are considered a global public health good to be preserved.
View Article and Find Full Text PDFLateral entry into general practice - an explorative analysis of general practice trainees in the competence centre for postgraduate medical education Baden-Württemberg.
GMS J Med Educ
December 2024
Heidelberg University Hospital, Department of General Medicine and Health Services Research, Heidelberg, Germany.
Objective: To aid the shortage of general practitioners (GPs) in Germany, since 2011 medical specialists from other fields may switch specialisation by undergoing a slim-lined training programme (lateral entry) into general practice (GP). Available published qualitative and quantitative data on lateral entrants (LEs) is scarce. Aim of the study was an explorative analysis of LEs in the competence centre for postgraduate medical education Baden-Wuerttemberg (KWBW).
View Article and Find Full Text PDFThe development of the Promoting First Relationships home visiting program and caregivers' comments about their experiences across four RCT studies.
Infant Ment Health J
December 2024
Child, Family, and Population Health Nursing, University of Washington, Seattle, Washington, USA.
Promoting First Relationships (PFR) is an evidence-based home-visiting program for caregivers and their children from birth to age 5 years. It focuses on caregiver-child interaction, attachment, and relationship quality using video feedback of unedited recordings to elicit reflection and provide positive feedback linked to knowledge development. This paper provides a brief history of PFR and reports on a qualitative study of 222 caregivers' comments about their PFR experiences following participation in one of four randomized controlled trials conducted over the past decade in the United States (two studies within child welfare setting, one study with Native American families, and one study with Spanish and English-speaking mothers), using a thematic analysis approach to code excerpts from written satisfaction surveys and oral satisfaction interviews.
View Article and Find Full Text PDFEffects of vagus nerve stimulation on daily function and quality of life in markedly treatment-resistant major depression: Findings from a one-year, randomized, sham-controlled trial.
Brain Stimul
December 2024
Medical University of South Carolina, Department of Psychiatry, Charleston, SC, USA.
Background: Depression treatments aim to minimize symptom burden and optimize quality of life (QoL) and psychosocial function.
Objective: Compare the effects of adjunctive versus sham vagus nerve stimulation (VNS) on QoL and function in markedly treatment-resistant depression (TRD).
Methods: In this multicenter, double-blind, sham-controlled trial, 493 adults with TRD and ≥4 adequate but unsuccessful antidepressant treatment trials (current episode) were randomized to active (n = 249) or sham (n = 244) VNS (plus treatment as usual) over a 12-month observation period.
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