Objective: Higher optimism has been linked with health, well-being, and cognitive functioning. Spouses also play an important role on people's health, especially in older adulthood. Yet, whether a spouse's optimism is associated with an individual's cognitive functioning is understudied. Thus, we examined this question.
Method: Participants were 4,457 heterosexual couples (N = 8,914; M = 66.73, SD = 9.67) from the Health and Retirement Study-a large, diverse, prospective, and nationally representative sample of U.S. adults aged >50. Optimism was assessed at baseline (t ) and cognition was measured every two years with up to five repeated assessments of cognition data over the 8-year follow-up period (t ; t ; t ; t ; t ).
Results: Results from multi-level dyadic data analyses showed small but positive associations between actor optimism and actor cognitive functioning (memory: r = .16, mental status = .10), as well as partner optimism and actor cognitive functioning (memory: r = .04, mental status = .03). These associations mostly persisted over time.
Conclusions: Participants' own optimism and their partner's optimism were both positively associated with cognitive functioning.Thus, with further research, optimism (at both the individual and couple level) might emerge as an innovative intervention target that helps adults maintain cognitive functioning as they age.
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http://dx.doi.org/10.1111/jopy.12529 | DOI Listing |
J Integr Neurosci
December 2024
Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06519, USA.
Background: The National Institutes of Health (NIH) Toolbox Cognition Battery is increasingly being used as a standardized test to examine cognitive functioning in multicentric studies. This study examines the associations between the NIH Toolbox Cognition Battery composite scores with neuroimaging metrics using data from the Adolescent Brain Cognitive Development (ABCD) study to elucidate the neurobiological and neuroanatomical correlates of these cognitive scores.
Methods: Neuroimaging data from 5290 children (mean age 9.
J Integr Neurosci
December 2024
Department of Radiology, The Affiliated Hospital of Hangzhou Normal University, 310015 Hangzhou, Zhejiang, China.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common metabolism-related multisystem clinical disorder, often accompanied by a high comorbidity of mild cognitive impairment (MCI). Increasing evidence suggests that the amygdala is crucial in cognitive processing during metabolic dysfunction. Nevertheless, the role of the amygdala in the neural mechanisms of MASLD with MCI (MCI_MASLD) remains unclear.
View Article and Find Full Text PDFJ Integr Neurosci
December 2024
Department of Human Anatomy, School of Basic Medical Sciences, Wannan Medical College, 241002 Wuhu, Anhui, China.
Background: K48-linked ubiquitin chain (Ub-K48) is a crucial ubiquitin chain implicated in protein degradation within the ubiquitin-proteasome system. However, the precise function and molecular mechanism underlying the role of Ub-K48 in the pathogenesis of Alzheimer's disease (AD) and neuronal cell abnormalities remain unclear. The objective of this study was to examine the function of K48 ubiquitination in the etiology of AD, and its associated mechanism of neuronal apoptosis.
View Article and Find Full Text PDFJ Integr Neurosci
December 2024
Department of Computer Science and Engineering, Shaoxing University, 312000 Shaoxing, Zhejiang, China.
Background: Motor imagery (MI) plays an important role in brain-computer interfaces, especially in evoking event-related desynchronization and synchronization (ERD/S) rhythms in electroencephalogram (EEG) signals. However, the procedure for performing a MI task for a single subject is subjective, making it difficult to determine the actual situation of an individual's MI task and resulting in significant individual EEG response variations during motion cognitive decoding.
Methods: To explore this issue, we designed three visual stimuli (arrow, human, and robot), each of which was used to present three MI tasks (left arm, right arm, and feet), and evaluated differences in brain response in terms of ERD/S rhythms.
J Integr Neurosci
December 2024
Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 637000 Nanchong, Sichuan, China.
Background: The relationship between subregion atrophy in the entire temporal lobe and subcortical nuclei and cognitive decline at various stages of Alzheimer's disease (AD) is unclear.
Methods: We selected 711 participants from the AD Neuroimaging Initiative (ADNI) database, which included 195 cases of cognitively normal (CN), 271 cases of early Mild cognitive impairment (MCI) (EMCI), 132 cases of late MCI (LMCI), and 113 cases of AD. we looked at how subregion atrophy in the temporal lobe and subcortical nuclei correlated with cognition at different stages of AD.
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