Purpose: To investigate volume changes of the gallbladder at computed tomography (CT) following bowel preparation for colonoscopy and to evaluate the incidence of gallbladder contraction at abdominal sonography performed with colonoscopy on the same day.
Methods: During a 1-year period, 222 patients underwent abdominal CT (CT) and colonoscopy on the same day. Among them, 123 patients had prior CT imaging without receiving colonoscopy in the past were enrolled. Manual estimates of 3D gallbladder volume were obtained from two CT scans to evaluate whether gallbladder volume changed as a result of bowel preparation for colonoscopy. During the same 1-year period, another 89 patients underwent abdominal sonography and colonoscopy on the same day (sonography group). The short-axis diameters of the gallbladder on the longitudinal scan of sonography from these patients were obtained.
Results: Gallbladder volume was significantly larger on prior CT without colonoscopy (31.7 ± 15.4 cm) than on CT (20.3 ± 11.1 cm) (p < 0.001). Gallbladder volume decreased by more than 50% in 41 of 123 patients (33%) who underwent abdominal CT and colonoscopy on the same day, compared with standard CT. In the sonography group (n = 89), the short-axis diameters of the gallbladder were less than 1.5 cm in 41 patients (46%) and less than 1.0 cm in 17 patients (19%).
Conclusion: Contracted gallbladder secondary to bowel preparation can be seen on imaging when performed with same-day colonoscopy. Such a situation may lead to the incomplete or inadequate evaluation of the gallbladder on imaging with same-day colonoscopy.
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http://dx.doi.org/10.1007/s00261-019-02345-0 | DOI Listing |
Contemp Clin Trials
December 2024
San Francisco VA Medical Center, United States of America; Department of Medicine, University of California, San Francisco, CA, United States of America; Measurement Science Quality Enhancement Research Initiative, San Francisco VA Healthcare System, United States of America. Electronic address:
Background: Colorectal cancer (CRC) prevention is a Veterans Affairs (VA) priority. Colonoscopy quality, especially adenoma detection rate (ADR), is critical for effective screening. Our research indicates considerable variation in ADR among VA providers.
View Article and Find Full Text PDFVaccine
December 2024
School of Life Science, Nanchang University, Nanchang 330031, China. Electronic address:
For a long time, grass carp culture in China has been severely affected by Grass Carp hemorrhagic disease caused by Grass Carp Reovirus (GCRV). At present, vaccines have been widely used for protecting aquatic organisms against infectious diseases, among which oral immunization with Lactobacillus casei is safe and highly effective. This vaccination route has the advantages of easy administration and noninvasive delivery.
View Article and Find Full Text PDFPLoS One
December 2024
The Third Faculty of Medicine, Charles University, Prague, Czech Republic.
Background: Exposure of critically ill patients to antibiotics lead to intestinal dysbiosis, which often manifests as antibiotic-associated diarrhoea. Faecal microbiota transplantation restores gut microbiota and may lead to faster resolution of diarrhoea.
Methods: Into this prospective, multi-centre, randomized controlled trial we will enrol 36 critically ill patients with antibiotic-associated diarrhoea.
Mar Drugs
December 2024
Key Laboratory of Marine Drugs of Ministry of Education, Shandong Key Laboratory of Glycoscience and Glycotechnology, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Oligoguluronate lithium (OGLi) was prepared for the purpose of enhancing the anti-ulcerative colitis (UC) activities of OG, in which lithium (Li) is coupled with the C6-carboxyl of G residue. The therapeutic effects of OGLi on dextran sulfate (DSS)-induced UC mice were investigated, and oligoguluronate sodium (OGNa) and lithium carbonate (LC) were used as contrasts. The effects of OGLi, OGNa and LC on the treatment of UC mice were studied by monitoring body weight change and evaluating colon length, the disease activity index (DAI), histopathological examination and gut microbiota regulation.
View Article and Find Full Text PDFReprod Biomed Online
October 2024
Virginia Center for Reproductive Medicine, Reston, VA, USA; Department of Obstetrics and Gynecology, George Washington University, Washington, DC, USA. Electronic address:
Research Question: How safe and effective is transrectal oocyte retrieval (TROR) for fertility preservation in nulliparous virginal women?
Design: This was a retrospective single-centre study of 105 nulliparous women from five satellite centres of Fakih IVF, UAE, who underwent TROR for oocyte cryopreservation. Extensive bowel preparation and rectal cleansing was performed prior to oocyte retrieval. Patient characteristics, stimulation protocol, and procedure outcome and safety data were collected.
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