Methods to make microcapsules - used in a broad range of healthcare and energy applications - currently suffer from poor size control, limiting the establishment of size/property relationships. Here, we use microfluidics to produce monodisperse polyurea microcapsules (PUMC) with a limonene core. Using varied flow rates and a commercial glass chip, we produce capsules with mean diameters of 27, 30, 32, 34, and 35 µm, achieving narrow capsule size distributions of ±2 µm for each size. We describe an automated method of sizing droplets as they are produced using video recording and custom Python code. The sustainable generation of such size-controlled PUMCs, potential replacements for commercial encapsulated systems, will allow new insights into the effect of particle size on performance.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884639 | PMC |
http://dx.doi.org/10.1038/s41598-019-54512-4 | DOI Listing |
Sci Rep
November 2019
Department of Chemistry and Materials Innovation Factory, University of Liverpool, Crown Street, Liverpool, L69 7ZD, UK.
Methods to make microcapsules - used in a broad range of healthcare and energy applications - currently suffer from poor size control, limiting the establishment of size/property relationships. Here, we use microfluidics to produce monodisperse polyurea microcapsules (PUMC) with a limonene core. Using varied flow rates and a commercial glass chip, we produce capsules with mean diameters of 27, 30, 32, 34, and 35 µm, achieving narrow capsule size distributions of ±2 µm for each size.
View Article and Find Full Text PDFFront Chem
May 2019
College of Chemistry and Chemical Engineering, University of Jinan, Jinan, China.
Owing to their high specific surface area and low density, porous polymer materials are of great importance in a vast variety of applications, particularly as supports for enzymes and transition metals. Herein, highly uniform and porous polyurea microspheres (PPM), with size between 200 and 500 μm, are prepared by interfacial polymerization of toluene diisocyanate (TDI) in water through a simple microfluidic device composed of two tube lines, in one of which TDI is flowing and merged to the other with flowing aqueous phase, generating therefore TDI droplets at merging. The polymerization starts in the tube while flowing to the reactor and completed therein.
View Article and Find Full Text PDFLangmuir
January 2015
Max Planck Institute for Dynamics and Self-Organization, Am Fassberg 17, 37077 Göttingen, Germany.
Interfacial polymerization techniques offer a versatile route for microcapsule synthesis. We designed a microfluidic process to synthesize monodisperse polyurea microcapsules (PUMCs); the microcapsules are formed by an interfacial polymerization of isocyanate dissolved in the oil and an amine dissolved in water. We measure the mechanical properties of the capsule as well as transport properties through the membrane using two microfluidic methods.
View Article and Find Full Text PDFLangmuir
November 2014
School of Engineering and Applied Sciences, Harvard University, 29 Oxford Street, Cambridge, Massachusetts 02138, United States.
We use microfluidics to continuously produce monodisperse polyurea microcapsules (PUMCs) having either aqueous or nonaqueous cores. The microcapsule shells are formed by the reaction between an isocyanate, dissolved in oil, and an amine, dissolved in water, at the surface of oil-in-water or water-in-oil drops immediately as they are formed. Different microcapsule morphologies can be generated using our approach.
View Article and Find Full Text PDFMacromol Rapid Commun
September 2011
Laboratory of Polymer Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands; Dutch Polymer Institute DPI, PO Box 902, 5600 AX Eindhoven, The Netherlands.
Via an isocyanate-free route, a series of segmented polyureas (PUs) were synthesized from (potentially) renewable resources. To the best of our knowledge, the present work shows for the first time that the organic superbase guanidine 1,5,7-triazabicyclododecene (TBD) which was originally developed as a catalyst for the ring-opening polymerization of lactones, lactides or cyclic carbonates, is also a promising catalyst for the transurethanization between dicarbamates and diamino-terminated poly(propylene glycol) (PPGda) providing PUs via an isocyanate-free strategy. The renewable segmented PUs contain monodisperse hard segments (HSs).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!