Study Objective: This study aims to systematically review the literature to evaluate the association between labor epidural analgesia (LEA) and postpartum depression (PPD).
Design: Meta-analysis.
Setting: Obstetric patients delivering vaginally with or without LEA in a hospital.
Interventions: This study aimed to investigate the effects of providing LEA on developing PPD.
Measurements: Pooled odds ratios (OR) and 95% confidence intervals (CI) were calculated using the random effects model.
Results: A total of 356 full text articles were reviewed. Eleven articles studying 85,928 patients met inclusion criteria. The pooled unadjusted OR 1.03 and 95% CI (0.77, 1.37) suggest that LEA is not associated with a decreased risk of developing PPD.
Conclusions: Labor epidural analgesia was not shown to confer protection against developing PPD according to this meta-analysis. Future studies are needed to explore whether other aspects of LEA, beyond its presence or absence, influence the onset of PPD.
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| http://dx.doi.org/10.1016/j.jclinane.2019.109658 | DOI Listing |
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