AI Article Synopsis
- Androgen-deprivation therapy (ADT) for prostate cancer negatively affects physical function and quality of life (QoL).
- A study was conducted where men on long-term ADT were divided into an intervention group receiving a structured lifestyle program and a control group, focusing on increasing physical activity and reducing sedentary behavior.
- The results showed that the intervention group experienced significant improvements in QoL and reductions in depression, along with increased physical activity levels while decreasing sedentary time compared to the control group.
Article Abstract
Androgen-deprivation therapy (ADT) for prostate cancer (PCa) is associated with reduced physical function and quality of life (QoL). We investigated the impact of a structured lifestyle intervention on the promotion of physical activity (PA) and reduction of sedentary behavior (SB), and its effect on QoL in men on ADT. Patients with advanced PCa on long-term ADT were randomized to the intervention (N = 11) or a control arm (N = 10) between February 2018 and May 2019. The intervention group received a structured lifestyle intervention including motivational text messages for 8 weeks (maintenance visit at week 12). At each visit, self-report measures and accelerometer data were used to assess PA and SB, and questionnaires were used to measure QoL, life satisfaction, anxiety, and depression. Significantly greater improvements in QoL and depression compared to baseline were reported in the intervention group compared to the control group. In addition, the intervention group also showed a significantly greater increase in self-reported light, as well as moderate-to-vigorous PA, and reduction in self-reported SB. Given its inherent advantage in improving QoL and reducing depression, a lifestyle intervention program should be offered to patients on ADT.
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| http://dx.doi.org/10.5993/AJHB.44.1.10 | DOI Listing |
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