Aflatoxins from the endophytic fungus Y-2 isolated from the critically endangered conifer .

Nat Prod Res

Department of Biological Medicines, School of Pharmacy, Fudan University, Shanghai, PR China.

Published: October 2021

Two new [asperxins A () and B ()] and four known (-) aflatoxins were isolated and identified from the endophytic fungus Y-2, which was derived from the needles of the critically endangered conifer . Their structures were elucidated by extensive spectroscopic methods. Among the isolates, compounds and showed considerable cytotoxicities against the A549 and Hela human cancer cell lines, with IC values in the range of 7.5-16.8 μM.

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http://dx.doi.org/10.1080/14786419.2019.1696328DOI Listing

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