Updates on Botulinum Neurotoxins in Dermatology.

Am J Clin Dermatol

University of Toronto, 2075 Bayview Ave M1 700, Toronto, ON, M4N 3M5, Canada.

Published: April 2020

AI Article Synopsis

  • Botulinum neurotoxin (BoNT) injections are the most popular non-surgical cosmetic treatment and are gaining attention from practitioners worldwide.
  • The article discusses new botulinum toxins in development or nearing market approval in the USA and Canada, such as daxibotulinumtoxin A, prabotulinumtoxin A, letibotulinumtoxin A, and botulinum toxin E.
  • These new neurotoxins, while similar in effectiveness, offer unique benefits like longer-lasting results, fewer animal-derived components, and quicker effects with shorter durations.

Article Abstract

Being the most popular non-surgical cosmetic procedure, botulinum neurotoxin (BoNT) injections are increasingly of interest to all cosmetic practitioners across the globe. This article serves to update readers on the new botulinum toxins that are currently in development or close to market in the USA and Canada, including daxibotulinumtoxin A, prabotulinumtoxin A, letibotulinumtoxin A, and botulinum toxin E. Despite having relatively similar characteristics and equivalent clinical efficacies, these neurotoxins manifest a multitude of unique potential advantages that will be explored in this review, including but not limited to a longer duration of action, the absence of animal-derived components or human albumin, and a rapid onset with short duration of action.

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Source
http://dx.doi.org/10.1007/s40257-019-00482-2DOI Listing

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