Background: Prevalence rates of infectious diseases in post-trial prisons have been scarcely investigated. Due to the specific characteristics of these prison populations, these prevalence rates may differ from pre-trial prisons and more information is needed for developing adequate prevention and treatment interventions. This study compared prevalence rates of hepatitis B virus (HBV), hepatitis C virus (HCV), susceptibility to varicella zoster virus (VZV) and measles in pre- and post-trial detention.
Methods: Data were collected in Geneva post-trial prisons among males (n=250), including serological tests, demographics, and risk factors, and were compared to those of the Geneva pre-trial prison (n=273).
Results And Conclusions: Incarcerated men in post-trial detention shared a disproportionate burden of infectious diseases compared to community (chronic HBV: 5.9%, HVC: 2.8%, susceptibility to VZV: 5.9%, to measles: 4.7%). Susceptibility to VZV and prevalence rate of HCV were lower in post-trial prisons (p=.034 and p=.080). Prevalence rates of infectious diseases in prison should be interpreted in light of the prison population's characteristics. Screening and treatment should be promoted in all types of prison settings. Since overcrowding and turnover of pre-trial prisons restrict the access to screening, prevention and treatment of infectious diseases, interventions are crucial in post-trial prisons.
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http://dx.doi.org/10.1016/j.jiph.2019.11.001 | DOI Listing |
Trends Microbiol
January 2025
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA; Princeton School of Public and International Affairs, Princeton University, Princeton, NJ, USA.
Serological studies uniquely strengthen infectious disease surveillance, expanding prevalence estimates to encompass asymptomatic infections, and revealing the otherwise inapparent landscape of immunity, including who is and is not susceptible to infection. They are thus a powerful complement to often incomplete epidemiological and public health measures (administrative measures of vaccination coverage, incidence estimates, etc.).
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Wuhan Third hospital, Tongren Hospital of Wuhan University, 241 Pengliuyang Road, Wuhan 430060, China. Electronic address:
Parkinson's disease (PD), a neurodegenerative disorder without cure, is characterized by the pathological aggregation of α-synuclein (α-Syn) in Lewy bodies. Classic deposition pathway and condensation pathway contribute to α-Syn aggregation, and liquid-liquid phase separation is the driving force for condensate formation, which subsequently undergo liquid-solid phase separation to form toxic fibrils. Traditional Chinese Medicine (TCM) has a long history in treating neurodegenerative disease, herein; we identified chemicals from herbs that inhibit α-Syn aggregation.
View Article and Find Full Text PDFJ Glob Antimicrob Resist
January 2025
Department of Medicine, Division of Clinical Infectious Diseases, Showa University School of Medicine, Tokyo, Japan.
Objectives: In Pseudomonas aeruginosa isolates, emerging meropenem resistance beyond imipenem resistance has become a problem. In this study, we aimed to investigate the relationship between the in vivo acquisition of antimicrobial resistance in fluoroquinolone- and carbapenem-resistant P. aeruginosa clinical isolates, the underlying molecular mechanisms, and exposure to antimicrobial agents.
View Article and Find Full Text PDFJ Glob Antimicrob Resist
January 2025
Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:
Piperacillin/tazobactam antimicrobial susceptibility testing (AST) against Enterobacterales can be challenging. The aim of this study was to assess the reproducibility of various automated (Vitek®2) and non-automated AST methods (broth microdilution (BMD), minimum inhibitory concentration (MIC) test strip, and disk diffusion) for piperacillin/tazobactam in 'challenging' E. coli isolates.
View Article and Find Full Text PDFNeurobiol Dis
January 2025
Department of Molecular Genetics & Microbiology, University of Florida College of Medicine, Gainesville, FL 32611, USA.
Abnormal tau phosphorylation is a key mechanism in neurodegenerative diseases. Evidence implicates infectious agents, such as Herpes Simplex Virus 1 (HSV-1), as co-factors in the onset or the progression of neurodegenerative diseases, including Alzheimer's disease. This has led to divergence in the field regarding the contribution of viruses in the etiology of neurodegenerative diseases.
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