Background: Postoperative ileus is a common complication following abdominal surgery. This study was undertaken to determine the effectiveness and safety of Cassia alata Linn in stimulating gastrointestinal function recovery among women with gynecologic cancer who had undergone laparotomy for surgical staging or cytoreductive surgery.
Methods: A total of 90 participants were randomly allocated to postoperative consumption of either Cassia alata Linn tea (n = 45) or warm water (N = 45). Outcomes of interest included time to first passage of flatus, time to first defecation, time to toleration of solid food, and ileus symptoms. Differences between the groups were measured as mean difference (MD) or odds ratio (OR) with 95% confidence interval (CI).
Results: Women allocated to the Cassia alata Linn group had shorter times to first passage of flatus (MD -8.53; 95% CI -3.69, -13.38 h) and first defecation (MD -19.83; 95% CI -11.18, -28.48 h) compared with controls. There were no differences in terms of time to toleration of solid food (MD 0.26; 95% CI -2.13, 1.61 h) or ileus symptoms (OR 0.10; 95% CI 0.01, 1.94) between the two groups.
Conclusion: Postoperative consumption of Cassia alata Linn hastens gastrointestinal function recovery after laparotomy in women with gynecologic cancer.
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http://dx.doi.org/10.1016/j.ctim.2019.102222 | DOI Listing |
Drug Des Devel Ther
October 2024
Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.
Linn is a popular herbal remedy in many countries, and its activities have been studied through many studies, starting from in silico, in vitro, and in vivo. This narrative review will focus more on secondary metabolites that are responsible for certain pharmacological activities that have undergone in vivo, in vitro, and in silico testing to determine the underlying mechanism. Twenty pharmacological activities have been identified, with the flavonoid group (emodin, kaempferol, quercetin) as the most prevalent secondary metabolite found in .
View Article and Find Full Text PDFComb Chem High Throughput Screen
October 2024
Department of Zoology, Faculty of Science, Tanta University, Tanta, Egypt.
Introduction: The concurrent presence of helminthiasis and bacterial diseases imposes a dual burden, worsening the challenges associated with each condition independently. This cohabitation intensifies the economic impact, creating a compounding effect on public health and economic well-being.
Method: Phytochemical analysis of Cassia alata Extract (CAE) using infrared spectroscopy has revealed the presence of various functional groups.
Plants (Basel)
September 2024
Instituto de Ecología Aplicada, Universidad Autónoma de Tamaulipas, Ciudad Victoria 87019, Mexico.
As part of the Fabaceae project of northeastern Mexico and based on field work, collection of botanical samples over the past 37 years, and reviewing botanical materials in national and international herbaria, the diversity of legumes of the subfamilies Caesalpinioideae (excluding tribe Mimoseae), Cercidoideae, and Detarioideae in northeastern Mexico has been recorded. New nomenclatural changes in tribes and genera of the subfamily Caesalpinioideae found in the new scientific bibliography are included. The subfamily Caesalpinioideae (excluding the tribe Mimoseae) includes five tribes: tribe Caesalpinieae, with eight genera (, , , , , , , and ) and 21 species; tribe Cassieae with three genera (, , and ) and 28 species; tribe Ceratonieae with one genus () and 1 species; tribe Gleditsieae with one genus () and 1 species.
View Article and Find Full Text PDFIran J Pharm Res
March 2024
Department of Pharmacognosy, Faculty of Pharmacy and Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Background: Vahl. () is a medicinal plant containing anthraquinone compounds such as sennoside. is primarily valued for its laxative properties.
View Article and Find Full Text PDFBioprocess Biosyst Eng
August 2024
Department of Biomedical Science and Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, 24341, Republic of Korea.
The most prevalent form of inflammatory bowel disease (IBD), ulcerative colitis (UC), is characterized by persistent inflammation of the colorectal mucosa. It is asymptomatic, whereas Crohn's disease (CD) causes patchy lesions in the gastrointestinal tract. Men and women suffer equally from ulcerative colitis, which usually strikes in the second and third decades of life and becomes more common in senior citizens.
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