The past decades have witnessed rapid urbanization around the world. This is particularly evident in Zhuhai City, given its status as one of the earliest special economic zones in China. After experiencing rapid urbanization for decades, the level of ecosystem health (ESH) in Zhuhai City has become a focus of attention. Assessments of urban ESH and spatial correlations between urbanization and ESH not only reveal the states of urban ecosystems and the extent to which urbanization affected these ecosystems, but also provide new insights into sustainable eco-environmental planning and resource management. In this study, we assessed the ESH of Zhuhai City using a selected set of natural, social and economic indicators. The data used include Landsat Thematic Mapper images and socio-economic data of 1999, 2005, 2009 and 2013. The results showed that the overall ESH value and ecosystem service function have been on the decline while Zhuhai City has continued to become more urbanized. The total ESH health level trended downward and the area ratio of weak and relatively weak health level increased significantly, while the areas of well and relatively well healthy state decreased since 1999. The spatial correlation analysis shows a distinct negative correlation between urbanization and ESH. The degree of negative correlation shows an upward trend with the processes of urban sprawl. The analysis results reveal the impact of urbanization on urban ESH and provide useful information for planners and environment managers to take measures to improve the health conditions of urban ecosystems.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926934 | PMC |
http://dx.doi.org/10.3390/ijerph16234717 | DOI Listing |
Adv Sci (Weinh)
December 2024
Innovation Center for Diagnostics and Treatment of Thalassemia, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China.
Despite the well-documented mutation spectra of β-thalassemia, the genetic variants and haplotypes of globin gene clusters modulating its clinical heterogeneity remain incompletely illustrated. Here, a targeted long-read sequencing (T-LRS) is demonstrated to capture 20 genes/loci in 1,020 β-thalassemia patients. This panel permits not only identification of thalassemia mutations at 100% of sensitivity and specificity, but also detection of rare structural variants (SVs) and single nucleotide variants (SNVs) in modifier genes/loci.
View Article and Find Full Text PDFJACS Au
December 2024
State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, No. 345 Lingling Road, Shanghai 200032, China.
Macrocyclization is a compelling strategy for conventional drug design for improving biological activity, target specificity, and metabolic stability, but it was rarely applied to the design of PROTACs possibly due to the mechanism and structural complexity. Herein, we report the rational design of the first series of "Head-to-Tail" macrocyclic PROTACs. The resulting molecule exhibited pronounced Brd4 protein degradation with low nM DC values while almost totally dismissing the "hook effect", which is a general character and common concern of a PROTAC, in multiple cancer cell lines.
View Article and Find Full Text PDFAdv Mater
December 2024
Centre for Quantum Physics, Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement (MOE), School of Physics, Beijing Institute of Technology, Beijing, 100081, China.
Through the stacking technique of 2D materials, the interfacial polarization can be switched by an interlayer sliding, known as sliding ferroelectricity, which is advantageous in ultra-thin thickness, high switching speed, and high fatigue resistance. However, uncovering the relationship between the sliding path and the polarization state in rhombohedral-stacked materials remains a challenge, which is the key to 2D sliding ferroelectricity. Here, layer-dependent multidirectional sliding ferroelectricity in rhombohedral-stacked InSe (γ-InSe) is reported via dual-frequency resonance tracking piezoresponse force microscopy and conductive atomic force microscopy.
View Article and Find Full Text PDFInt Urogynecol J
December 2024
Department of Ultrasound, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, Guangdong, China.
Introduction And Hypothesis: This study examines the effectiveness of yoga intervention on the early postpartum recovery of pelvic organ positions.
Methods: A prospective study was conducted from May to November 2020, involving women who had vaginal deliveries and underwent pelvic floor ultrasound examinations. The control group received no intervention, whereas the experimental group participated in weekly 60-min yoga sessions from 1 week to 3 months postpartum.
Laryngoscope
December 2024
Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!