AI Article Synopsis

  • The report discusses a rare case of gingival plasma cell granuloma (PCG) in a 60-year-old hypertensive woman on Amlodipine, highlighting its unique presentation.
  • The importance of thorough investigations is emphasized for accurate diagnosis, especially when considering drug-induced gingival overgrowth as a potential cause.
  • Histopathology analysis confirmed the diagnosis of PCG, differentiating it from other conditions like gingival overgrowth and fibroma.

Article Abstract

The aim of the present report was to discuss a unique case of gingival plasma cell granuloma (PCG) in a hypertensive patient on Amlodipine therapy. Also, we attempt to emphasize the importance of considering primary and advance investigations before making a definite diagnosis. PCG is an extremely rare, reactive, non-neoplastic lesion characterized by the predominance of polyclonal plasma cells. Drug-induced gingival overgrowth is a known side effect of Amlodipine. A hypertensive 60-year-old female patient reported with a chief complaint of swollen gums and discomfort in the upper front teeth region. A provisional diagnosis of Amlodipine-induced gingival overgrowth, combined gingival overgrowth, and fibroma was suggested. Surprisingly, histopathology revealed it to be a plasma cell lesion which was confirmed by advanced investigations, thereby establishing a confirmatory diagnosis of PCG.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874842PMC
http://dx.doi.org/10.18502/fid.v16i2.1366DOI Listing

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