We describe a case of acute liver failure and myopericarditis due to herpes simplex virus-1 (HSV-1) in an immunocompetent adult. We estimate that, at the height of viremia, the patient contained a quantity of HSV-1 virions approaching that of human cells. The patient recovered with acyclovir that was dose-adjusted for neurotoxicity and developed a vigorous anti-HSV-1 T-cell response.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868424PMC
http://dx.doi.org/10.1093/ofid/ofz465DOI Listing

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