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Massive pheochromocytoma causing adrenal crisis during surgery: a case report and review of the literature.
J Med Case Rep
March 2025
Department of Anesthesiology, West China Hospital of Sichuan University Ziyang Hospital, Zi Yang, Si Chuan, China.
Background: Pheochromocytoma is a rare adrenal medulla tumor that overproduces catecholamines, causing major cardiovascular issues. It is often found incidentally during imaging, but large tumors pose unique perioperative challenges. Patients are usually symptom-free until the tumor grows, risking an adrenergic crisis during surgery.
View Article and Find Full Text PDFBidirectional Ventricular Tachycardia due to Pheochromocytoma: A Case Report.
Ann Noninvasive Electrocardiol
March 2025
Xiamen Cardiovascular Hospital, Division of Cardiology, Xiamen University, Xiamen, Fujian, China.
Pheochromocytoma, a type of neuroendocrine tumor, can cause numerous symptoms and signs similar to those of other clinical conditions, with the classic triad being palpitations, headache, and diaphoresis. Patients with pheochromocytoma can present with various cardiac complications, including myocarditis, acute coronary syndromes, cardiomyopathy, heart failure, and arrhythmias. Here we report a case of pheochromocytoma that first presented with bidirectional ventricular tachycardia.
View Article and Find Full Text PDFPreoperative Management of Catecholamine-Producing Pheochromocytomas and Paragangliomas-Results From a DELPHI Process.
J Endocr Soc
March 2025
Department of Internal Medicine IV, University Hospital Munich, Munich 80336, Germany.
Context: European and German consensus guidelines advocate preoperative therapy with α-adrenoreceptor antagonists in symptomatic patients with catecholamine-producing pheochromocytomas and paragangliomas (PPGLs) to avoid hypertensive crisis during adrenalectomy. This practice has been questioned recently.
Objective: This work aimed to assess current preoperative management of PPGLs across disciplines.
People with Adrenal Insufficiency who are in Adrenal Crisis are Frequently Unable to Self-Administer Rescue Injections.
Endocr Pract
March 2025
Division of Rheumatology, Department of Medicine, National Jewish Health, Denver CO. USA. Electronic address:
Objectives: Individuals with adrenal insufficiency (AI) are at risk of acute adrenal crisis and death, particularly during illness or trauma, and may require rapid treatment with parenteral glucocorticoid such as hydrocortisone (HC) to manage a crisis. Current guidelines recommend timely self-injection in an evolving crisis. Little is known about the patient experience with emergency injections.
View Article and Find Full Text PDFTime Adjustment of Hydrocortisone Doses During Shift Work in Patients with Adrenal Insufficiency.
Horm Metab Res
March 2025
Endocrinology, Endocrinology in Charlottenburg, Berlin, Germany.
Shift work causes a disruption between the circadian system and the external light-dark cycle, but also a misalignment between various levels of the circadian system. There is no information on patients with adrenal insufficiency (AI) who are working shifts. The objective of the study was to analyze the hormone replacement therapy with hydrocortisone (HC) and the adaptation scheme in patients with AI on shifts.
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