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http://dx.doi.org/10.1165/rcmb.2019-0263LE | DOI Listing |
PLoS One
January 2025
Department of Psychological and Behavioural Science, London School of Economics, London, United Kingdom.
Conversational repair has been proposed as a universal system for maintaining mutual understanding during social interactions. The repair system has been studied extensively in offline synchronous interactions (e.g.
View Article and Find Full Text PDFComput Struct Biotechnol J
December 2024
Division of Pathology, European Institute of Oncology IRCCS, Milan, Italy.
The tumor suppressor is frequently mutated in hormone receptor-negative, HER2-positive breast cancer (BC), contributing to tumor aggressiveness. Traditional ancillary methods like immunohistochemistry (IHC) to assess functionality face pre- and post-analytical challenges. This proof-of-concept study employed a deep learning (DL) algorithm to predict mutational status from H&E-stained whole slide images (WSIs) of BC tissue.
View Article and Find Full Text PDFiScience
November 2024
Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215004, China.
Nucleus pulposus (NP) resides in hypoxic microenvironment and NP cells (NPCs), primarily reply on glycolysis and producing high levels of lactate. Intracellular lactate drives lysine lactylation (Kla) as a newly epigenetic modification. However, the impact of Kla on NPCs remains unknown.
View Article and Find Full Text PDFEur J Intern Med
January 2025
Amsterdam UMC location University of Amsterdam, Nephrology, Meibergdreef 9, Amsterdam, The Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands. Electronic address:
Aliment Pharmacol Ther
October 2024
Department of Gastroenterology, School of Translational Medicine, Monash University and Alfred Health, Melbourne, Victoria, Australia.
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