Purpose: To investigate associations between older drivers' perceived vision-related night-driving difficulties and night-time driving performance measured on a closed-road circuit.
Methods: Participants included 26 older drivers (71.8 ± 6.3 years) who reported vision-related night-driving difficulties assessed with the vision and night driving questionnaire (VND-Q). High-contrast, photopic visual acuity (VA) and ratings of discomfort glare (de Boer scale) were also assessed. Night-time driving performance was measured on a closed-road circuit that involved recognition, hazard avoidance and lane-keeping tasks in the absence and presence of intermittent glare. Generalized linear mixed models investigated the relationship between VND-Q scores and overall driving performance scores, as well as with discomfort glare ratings and VA.
Results: Greater levels of vision-related night-driving difficulties (VND-Q scores) were significantly associated with poorer night-driving performance (p = 0.003); the association was even stronger for driving performance in the presence of intermittent glare (p = 0.001). Reduced VA was associated with poorer night-driving performance (p = 0.022) but the association was weaker than for the VND-Q scores. In contrast, ratings of discomfort glare were not significantly associated with driving performance (p = 0.14).
Conclusion: The VND-Q was significantly associated with night-time driving performance and provides a useful instrument for assessing vision-related night-driving difficulties which can be incorporated into clinical vision assessments.
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http://dx.doi.org/10.1111/aos.14311 | DOI Listing |
This study investigated two cases. Case 1 involves a 53-year-old man who suffered from sleep apnea syndrome at age 48. Moreover, he was involved in a rear-end collision while driving and was admitted to the hospital at age.
View Article and Find Full Text PDFSci Total Environ
January 2025
Leiden University, Institute of Environmental Science - Industrial Ecology, Van Steenisgebouw, Einsteinweg 2, 2333 CC Leiden, the Netherlands. Electronic address:
In this study, we compared the Sol-Char sanitation system with an Anaerobic Digestion (AD) system using Life Cycle Assessment (LCA) to evaluate their environmental impacts. Since both systems offer opportunities for human waste treatment and resource recovery, understanding their performance is crucial. This comparison aims to determine their environmental impacts while considering diverse factors, such as energy production and nutrient recovery.
View Article and Find Full Text PDFSci Rep
January 2025
Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4515 McKinley Ave., St. Louis, MO, 63110, USA.
Functional magnetic resonance imaging (fMRI) has dramatically advanced non-invasive human brain mapping and decoding. Functional near-infrared spectroscopy (fNIRS) and high-density diffuse optical tomography (HD-DOT) non-invasively measure blood oxygen fluctuations related to brain activity, like fMRI, at the brain surface, using more-lightweight equipment that circumvents ergonomic and logistical limitations of fMRI. HD-DOT grids have smaller inter-optode spacing (~ 13 mm) than sparse fNIRS (~ 30 mm) and therefore provide higher image quality, with spatial resolution ~ 1/2 that of fMRI, when using the several source-detector distances (13-40 mm) afforded by the HD-DOT grid.
View Article and Find Full Text PDFCell Death Dis
January 2025
NHC Key Laboratory of Advanced Reproductive Medicine and Fertility (China Medical University), National Health Commission, Shenyang, 110004, China.
Metabolic rewiring underlies effective macrophages defense to respond disease microenvironment. However, the underlying mechanisms driving metabolic rewiring to enhance macrophage effector functions remain unclear. Here, we demonstrated that the metabolic reprogramming in inflammatory macrophages depended on the acetylation of CLYBL, a citramalyl-CoA lyase, at lysine 154 (K154), and blocking CLYBL-K154 acetylation restricted the release of pro-inflammatory factors.
View Article and Find Full Text PDFAcad Radiol
January 2025
Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110 (S.I., M.A.T., M.I., C.S., R.L., A.H., R.L.W., T.J.F.). Electronic address:
Rationale And Objective: Conventional positron emission tomography (PET) respiratory gating utilizes a fraction of acquired PET counts (i.e., optimal gate [OG]), whereas elastic motion correction with deblurring (EMCD) utilizes all PET counts to reconstruct motion-corrected images without increasing image noise.
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