We have developed a robust optimization approach for intensity modulated proton therapy treatment plans with multi-isocenter large fields. The method creates a low-gradient field dose in the junction regions to mitigate the impact caused by misalignment errors and is more efficient than the conventional junction shifting technique.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6871617PMC
http://dx.doi.org/10.14338/IJPT-16-00012.1DOI Listing

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