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Higher incidence of postoperative complications in patients with simultaneous patellar tendon and anterior cruciate ligament ruptures following single surgery: a case series and literature review.
BMC Musculoskelet Disord
January 2025
Department of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing, China.
Background: Patients with simultaneous ruptures of the patellar tendon (PT) and anterior cruciate ligament (ACL) underwent PT repair and ACL reconstruction in a single or staged surgery. However, due to the limited cases, the design of previous studies was mostly case report with varying conclusions regarding recommended surgical strategy selection, the optimal surgical strategy remains a subject of debate.
Methods: We conducted a retrospective case series and literature review, including 10 cases from local institution and 27 cases from 17 studies.
The Landmark Series: Neoadjuvant Radiotherapy in Extremity Soft Tissue Sarcoma-The Way to Hypofractionation.
Ann Surg Oncol
January 2025
Department of Radiotherapy and Physics, The Royal Marsden Hospital and The Institute of Cancer Research, London, UK.
For patients with nonmetastatic soft tissue sarcoma (STS) who are at high risk of local recurrence, the standard of care for limb-conserving local management is combined radiotherapy and surgery. Radiotherapy for STS entails 5 weeks of conventionally fractionated radiotherapy (25 × 2 Gy) preoperatively or 6 or more weeks postoperatively. There is growing interest in the use of preoperative hypofractionated regimes, viz.
View Article and Find Full Text PDFGerbils without Borders: Invasiveness, Plague, and Micro-Global Histories of Science, 1932-1939.
J Hist Med Allied Sci
January 2025
University of St Andrews, Scotland, UK.
In the 1930s, a series of bubonic plague outbreaks among humans cropped up in several villages at the border of Angola and Namibia. These outbreaks provoked deep concern, laying bare social and political tensions amongst neighboring imperial powers and Indigenous people within the region. Despite the appearance of this disease in what was then considered a recondite place, its spread sparked debate in transnational forums, such as the League of Nations and the Office International d'Hygiène Publique.
View Article and Find Full Text PDFAbout the ozone ability in using adaptive chaos to restore a healthy state in the oxygen-ozone adjunct therapy.
Int Immunopharmacol
December 2024
Italian Scientific Society of Oxygen-Ozone Therapy (SIOOT) and High Master School of Oxygen-Ozone Therapy, University of Pavia, Italy.
The action of ozone in medicine is a subject of interest and lively, controversial debates. Its mechanisms of action are still far from fully understood. However, it is possible that ozone triggers a series of dynamics in living organisms related to chaos, multi-stable phenomena, and oscillatory processes.
View Article and Find Full Text PDFMortality reduction with 23-valent pneumococcal polysaccharide vaccine: a systematic review and meta-analysis.
Pneumonia (Nathan)
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School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India.
Background: Pneumococcal disease, caused by Streptococcus pneumoniae, imposes a significant global health burden, particularly affecting vulnerable groups such as the elderly and immunocompromised. The 23-valent pneumococcal polysaccharide vaccine (PPV23) is designed to protect against 23 serotypes of Streptococcus pneumoniae. However, there is ongoing debate about its effectiveness in reducing all-cause mortality.
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