Changes in the population structure of influenza B virus in the Ukraine since 1980 has been studied. New strains of the virus have been identified and the epidemic potentials of different strains have been compared. The data on the drift mechanism of the origin of the intermediate strains of influenza B virus have been observed. A suggestion on the etiological prognostication of the epidemic process has been made.
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Front Immunol
January 2025
Immunology Research Center, National Health Research Institute, Zhunan, Taiwan.
CASK, a MAGUK family scaffold protein, regulates gene expression as a transcription co-activator in neurons. However, the mechanism of CASK nucleus translocation and the regulatory function of CASK in myeloid cells remains unclear. Here, we investigated its role in H5N1-infected macrophages.
View Article and Find Full Text PDFFront Vet Sci
January 2025
Department of Microbiology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.
Introduction: Cormorants, as protected wild animals by the State Forestry Administration of China, have a broad distribution across China. Previous studies have shown that they can be infected with multiple viruses in the , , , and families. There is limited knowledge about the other viruses that cormorants may carry and infect.
View Article and Find Full Text PDFFront Vet Sci
January 2025
Departamento de Medicina Preventiva Animal, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago, Chile.
Influenza A virus (IAV) continuously threatens animal and public health globally, with swine serving as a crucial reservoir for viral reassortment and evolution. In Chile, H1N2 and H3N2 subtypes were introduced in the swine population before the H1N1 2009 pandemic, and the H1N1 was introduced from the H1N1pdm09 by successive reverse zoonotic events. Here, we report two novel introductions of IAV H3N2 human-origin in Chilean swine during 2023.
View Article and Find Full Text PDFJ Trop Med
January 2025
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Silymarin is a polyphenolic flavonoid extracted from milk thistle. It has potent immunomodulatory effects and can inhibit the replication of influenza A virus (IAV). The present study aimed to determine the inflammatory and anti-inflammatory cytokine secretion patterns in mice before and after silibinin treatment.
View Article and Find Full Text PDFHeliyon
January 2025
National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Background: Previous studies have found an association between influenza, cardiovascular and cerebrovascular disease mortality, and all-cause mortality. And the vaccination of elderly diabetes is often recommended to reduce the risk of hospitalization and death. Nevertheless, no previous work has investigated the short-term impact of influenza on diabetes mortality in China.
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