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Small-Sample Learning for Next-Generation Human Health Risk Assessment: Harnessing AI, Exposome Data, and Systems Biology.
Environ Sci Technol
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Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
Metagenome-assembled genome of from urban bats in China.
Microbiol Resour Announc
December 2024
China National Center for Bioinformation, Beijing, China.
We conducted metagenomic sequencing on a stool sample collected from urban-dwelling and obtained a metagenome-assembled genome of . Phylogenetic analysis revealed that this strain is closely related to the one isolated from dogs, forming a distinct clade separate from the reference genome.
View Article and Find Full Text PDFEarly Identification of Myocardial Microstructural Alterations in Hypertrophic Cardiomyopathy with in Vivo Cardiac Diffusion-Tensor Imaging.
Radiol Cardiothorac Imaging
February 2025
From the Department of Magnetic Resonance Imaging, Radiology Imaging Center, Fuwai Hospital, National Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beilishi Road No. 167, Xicheng District, Beijing 100037, China (Z.D., Y.T., G.Y., X.M., S.Y., J.W., X.X., K.Y., M.L., X.C., S.Z.); Clinical and Technical Support, Philips Healthcare, Beijing, China (P.S.); and Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, SZ University Town, Shenzhen, China (K.Z., Y.Z.).
Purpose To explore the diffusion characteristics of hypertrophic cardiomyopathy (HCM) using in vivo cardiac diffusion-tensor imaging (cDTI) and to determine whether cDTI could help identify abnormal myocardium beyond cardiac MRI findings of fibrosis and hypertrophy. Materials and Methods In this prospective study conducted from April to August 2023, participants with HCM and healthy volunteers were enrolled for cardiac MRI evaluation, including cine, late gadolinium enhancement (LGE), T1 mapping, and cDT imaging, using a 3.0-T scanner.
View Article and Find Full Text PDFAge-Related Dynamics and Spectral Characteristics of the TCRβ Repertoire in Healthy Children: Implications for Immune Aging.
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National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Infection and Immunity, Chongqing, China.
T-cell receptor (TCR) diversity is crucial for adaptive immunity, yet baseline characterizations in pediatric populations remain sparse. We sequenced the TCRβ chain of 325 healthy Chinese children aged 0-18, categorized into six age groups. We also analyzed cellular composition and TCRβ associations using flow cytometry in 81 of these samples.
View Article and Find Full Text PDFEpitaxial Stabilization of a Pyrochlore Interface between Weyl Semimetal and Spin Ice.
Nano Lett
January 2025
Department of Physics and Astronomy, Rutgers University, Piscataway, New Jersey 08854, United States.
Pyrochlore materials are known for their exotic magnetic and topological phases arising from complex interactions among electron correlations, band topology, and geometric frustration. Interfaces between different pyrochlore crystals characterized by complex many-body ground states hold immense potential for novel interfacial phenomena due to the strong interactions between these phases. However, the realization of such interfaces has been severely hindered by limitations in material synthesis methods.
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