AI Article Synopsis
- The study examined the effectiveness of low concentration sodium hypochlorite (NaOCl) activated by Er,Cr:YSGG laser against biofilms in root canals, aiming to find safer disinfection methods for endodontic infections.
- Results showed that the combination of 0.5% NaOCl with laser treatment significantly decreased bacterial counts, comparable to 2.5% NaOCl used without laser activation.
- The findings suggest that using lower concentrations of NaOCl, enhanced by laser activation, could effectively treat infections while minimizing possible side effects.
Article Abstract
The onset and persistence of endodontic infections due to residual biofilm after chemical disinfection promotes secondary bacterial infection. Alternative methods to disinfect operated root canals are a matter of great interest. The aim was to evaluate the antibacterial effectiveness of sodium hypochlorite (NaOCl) at low concentrations activated by the Er,Cr:YSGG laser-activated irrigation (LAI) against 10-day-old intracanal biofilm. Biofilms were formed inside the root canals and divided into 7 groups (n13): 0.5% NaOCl + Er,Cr:YSGG; Saline + Er,Cr:YSGG; 0.5% NaOCl + syringe irrigation(SI); 2.5% NaOCl + SI; 5% NaOCl + SI; positive and negative controls. Bacterial survivors were counted and specimens visualized under scanning electron and confocal laser scanning microscopy. Treatments with 0.5% NaOCl + Er,Cr:YSGG and 2.5% NaOCl + SI gave a significant reduction in the number of CFU/mm. Moreover, scanning electron microscopy and confocal laser scanning microscopy imaging confirmed and reinforced bacteriological data. Thus, Er,Cr:YSGG LAI proved to be able to improve the intracanal distribution of 0.5% NaOCl after 60 s of activation, reaching the same level of effectiveness than 2.5% NaOCl. This is regarded as of clinical interest, since working with lower concentrations may contribute to reduce undesired effects.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963469 | PMC |
| http://dx.doi.org/10.3390/antibiotics8040232 | DOI Listing |
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