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Insulin degludec 100 U/mL for treatment of spontaneous diabetes mellitus in dogs.

J Vet Intern Med

January 2025

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.

Background: The advantages of insulin degludec 100 U/mL (IDeg100) in the treatment of diabetes mellitus (DM) include consistent release, predictable glucose-lowering effect, and minimal day-to-day variability.

Hypothesis/objectives: To describe the use of IDeg100 in dogs with DM, level of diabetic control and adverse effects.

Animals: Thirty-three client-owned dogs with DM.

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Letter: Enhancing HCC Surveillance-GES Represents an Innovative Simple Effective Tool for Risk Stratification, Patient Safety and Reduced Anxiety.

Aliment Pharmacol Ther

January 2025

World Hepatitis Alliance Afro Regional Board Member, Honour President Saafara Hépatites Sénégal, Dakar, Senegal.

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The gut microbiota predicts and time-restricted feeding delays experimental colitis.

Gut Microbes

December 2025

Department of Microbiome Research and Applied Bioinformatics, Institute for Nutritional Sciences, University of Hohenheim, Stuttgart, Germany.

The etiology of inflammatory bowel disease (IBD) remains unclear, treatment options unsatisfactory and disease development difficult to predict for individual patients. Dysbiosis of the gastrointestinal microbiota and disruption of the biological clock have been implicated and studied as diagnostic and therapeutic targets. Here, we examine the relationship of IBD to biological clock and gut microbiota by using the IL-10 deficient () mouse model for microbiota-dependent spontaneous colitis in combination with altered (4 h/4 h) light/dark cycles to disrupt and time-restricted feeding (TRF) to restore circadian rhythmicity.

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Colorectal cancer (CRC) represents a significant global health challenge, with approximately 1.8 million new cases diagnosed annually and a mortality toll exceeding 881,000 lives each year. This study aimed to evaluate the chemoprotective efficacy of Cyanidin-3-glucoside (C3G) in a rat model of CRC induced by 1,2-dimethylhydrazine (DMH).

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Introduction: Although primary tumors of the brachial plexus (BP) are rare, schwannomas are the most frequently encountered type. This study evaluated the clinicopathological presentation, surgical outcomes, and prognosis of patients with BP schwannomas.

Methods: A systematic review was conducted using PubMed/MEDLINE, Embase, and Cochrane on the 25th of March 2024.

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