The family Parvoviridae includes an ample and most diverse collection of viruses. Exploring the biological diversity and the inherent complexity in these apparently simple viruses has been a continuous commitment for the scientific community since their first discovery more than fifty years ago. The Special Issue of 'Viruses' dedicated to the 'New Insights into Parvovirus Research' aimed at presenting a 'state of the art' in many aspects of research in the field, at collecting the newest contributions on unresolved issues, and at presenting new approaches exploiting systemic (-omic) methodologies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893750 | PMC |
| http://dx.doi.org/10.3390/v11111053 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Porcine parvovirus infection induces necroptosis of porcine placental trophoblast cells via a ZBP1-mediated pathway.
Vet Res
November 2024
College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Porcine parvovirus (PPV) infection induces germ cell death, leading to reproductive disorders in first-pregnant sows. Porcine placental trophoblast cells (PTCs) are the major target of PPV, and we have previously found that PPV infection leads to the death of PTCs by a non-apoptotic process, which may be related to PPV pathogenicity. The Z-nucleic acid-binding protein 1 (ZBP1) is often activated after virus invasion and mediates subsequent cell death.
View Article and Find Full Text PDFPositivity Status and Molecular Characterization of Porcine Parvoviruses 1 Through 8 (PPV1-PPV8) from Slaughtered Pigs in China.
Animals (Basel)
November 2024
College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Porcine parvoviruses one through eight (PPV1-PPV8) are prevalent in Chinese swine herds. However, the infection status of all these PPVs in slaughtered pigs is still unclarified. In this study, we detected PPV1-PPV8 in 353 tissue samples collected from slaughtered pigs from six regions of China in 2023.
View Article and Find Full Text PDFMinute virus of mice NS1 redirects casein kinase 2 specificity to suppress the ATR DNA damage response pathway during infection.
J Virol
December 2024
Department of Molecular Microbiology and Immunology, University of Missouri-Columbia, School of Medicine, Bond Life Sciences Center, Columbia, Missouri, USA.
Unlabelled: During infection the autonomous parvovirus minute virus of mice (MVM) generates extensive DNA damage which facilitates virus replication and induces a cellular DNA damage response (DDR) driven by the ataxia telangiectasia mutated (ATM) kinase. Atypically, the ataxia telangiectasia and Rad-3-related (ATR) DDR pathway remains inactive. Upon DNA damage ATR is normally recruited to single-stranded DNA sequences formed at genomic DNA damage sites, and while within a multiprotein complex activates, via phosphorylation, the key DDR regulator checkpoint kinase 1 (Chk1).
View Article and Find Full Text PDFCalcium and magnesium abnormalities in puppies with parvoviral enteritis.
Am J Vet Res
November 2024
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
Objective: To determine the association between ionized calcium (iCa) and/or total magnesium (tMg) and the development of sepsis and to investigate whether iCa or tMg is associated with mortality in puppies with canine parvoviral enteritis (CPE).
Methods: 64 client-owned puppies with CPE were enrolled in this prospective cohort study. Serum iCa and tMg were measured daily from admission until death or discharge.
The 2024 Outbreak of Parvovirus B19 as a Global Obstetrical Threat Insights From an Obstetrics Referral Center in Northern Italy.
J Med Virol
November 2024
Department of Maternity and Childhood, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
A significant increase in Parvovirus B 19 (B19V) infections has been reported in the last months in some European countries. This outbreak could be highly detrimental for pregnant women, considering the capacity of the virus to harm the fetus. However, the magnitude and spread of this outbreak is yet unclear.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!