Cellular Spindled Histiocytic Pseudotumor: A Benign Mimic of Spindle Cell Neoplasia of the Breast.

Arch Pathol Lab Med

From the Department of Pathology, Michigan Medicine, Ann Arbor.

Published: December 2019

Context.—: Cellular spindled histiocytic pseudotumor (CSHPT) is an exuberant, dense histiocytic proliferation seen in the setting of mammary fat necrosis. CSHPT has a broad histologic differential diagnosis, including benign, malignant, and inflammatory etiologies.

Objectives.—: To highlight the most important histologic and immunohistochemical findings of CSHPT and provide comparisons to entities within the broad differential diagnosis.

Data Sources.—: Recently published literature regarding CSHPT and other diagnostic considerations.

Conclusions.—: CSHPT is a benign histiocytic proliferation with a broad differential diagnosis, for which comprehensive ancillary studies may be required to exclude malignant and infectious entities.

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Source
http://dx.doi.org/10.5858/arpa.2019-0421-RADOI Listing

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