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Management of Preoperative Recipient Portal Vein Thrombosis in Living-donor Liver Transplantation.
J Clin Exp Hepatol
November 2024
Aster Integrated Liver Care, Aster Medcity, Cheranallur, Kochi 682027, India.
Portal vein thrombosis (PVT) occurs as a part of the natural history of cirrhosis in up to 15% of patients with cirrhosis. In the initial days, PVT was considered a contraindication to liver transplantation, but now with advanced techniques and perioperative management, patients with complex PVT also undergo living-donor liver transplantation (LDLT) with a similar outcome. This review provides a comprehensive overview of methods to proceed with liver transplantation when the recipient has PVT.
View Article and Find Full Text PDFWhat motivates critical care nurses to stay in their job? - Structural aspects for empowering intrinsic motivation in permissive professional contexts: A scoping review.
Intensive Crit Care Nurs
January 2025
Department of Psychosomatic Medicine and Psychotherapy, Professorship for Spiritual Care and Psychosomatic Health, University Hospital Rechts der Isar, Technical University of Munich, Kaulbachstraße 22a, Munich 80539, Germany.
Objective: In the wake of the COVID-19 pandemic, a significant number of critical care nurses have left their positions, citing overload, burnout, and moral distress. This scoping review is not just a theoretical exploration but a timely and crucial investigation into the aspects and structures of critical care nursing that can make the job fulfilling and appealing, thereby promoting intrinsic motivation and staff retention.
Methodology: A scoping review of studies reporting on factors that allow critical care nurses to fall back on their intrinsic job motivation.
Hospital-level volume in extracorporeal membrane oxygenation cases and death or disability at 6 months.
Crit Care Resusc
December 2024
Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia.
Objective: Extracorporeal membrane oxygenation (ECMO) is a high-risk procedure with significant morbidity and mortality and there is an uncertain volume-outcome relationship, especially regarding long-term functional outcomes. The aim of this study was to examine the association between ECMO centre volume and long-term death and disability outcomes.
Design Setting And Participants: This is a registry-embedded observational cohort study.
Novel high-content and open-source image analysis tools for profiling mitochondrial morphology in neurological cell models.
SLAS Discov
January 2025
Denali Therapeutics Inc., South San Francisco, CA 94080 USA.
Mitochondria undergo dynamic morphological changes depending on cellular cues, stress, genetic factors, or disease. The structural complexity and disease-relevance of mitochondria have stimulated efforts to generate image analysis tools for describing mitochondrial morphology for therapeutic development. Using high-content analysis, we measured multiple morphological parameters and employed unbiased feature clustering to identify the most robust pair of texture metrics that described mitochondrial state.
View Article and Find Full Text PDFArticle Synopsis
- This scoping review explores how "weight-related evidence" is defined and understood by Canadian Registered Dietitians, examining their perceptions, experiences, and knowledge regarding body size, fatness, and obesity in nutrition care.
- Based on a rigorous methodology, including a search across four main databases and grey literature, the review analyzed 2217 initial results and included 67 relevant studies, finding varied insights into the role of weight-related evidence across different aspects of nutrition assessment and interventions.
- The findings highlight the need for ongoing dialogue about weight-related issues in dietetics, providing a foundation for future research on dietitian-led interventions and suggesting that these Canadian insights could inform a broader international perspective.
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