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The Relationships of High-Sensitivity C-Reactive Protein and Homocysteine Levels With Disease Activity, Damage Accrual, and Cardiovascular Risk in Systemic Lupus Erythematosus. | LitMetric

Results: hs-CRP correlated significantly with SLEDAI-2K ( = .036), SDI ( = .00), anti-dsDNA titers ( = .034), diabetes ( = .005), and obesity ( = .027). hs-CRP and Hcy correlated with triglyceride (TG) levels ( = .032 and < .001, respectively), TG/high-density lipoprotein cholesterol index ( = .020 and = .001, respectively), and atherogenic index of plasma ( = .006 and = .016, respectively). hs-CRP levels >3 mg/L correlated with SDI score ( = .012) and several CVD risk factors.

Discussion: Findings suggest SLE patients with elevated hs-CRP and/or Hcy have a higher prevalence of CVD risk factors.

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http://dx.doi.org/10.1177/1099800419889192DOI Listing

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