Graves' disease and mental disorders.

J Clin Transl Endocrinol

Department of Diabetes, Metabolism and Endocrinology, Osaka Medical College, Japan.

Published: March 2020

AI Article Synopsis

  • Mental disorders are often seen alongside thyroid diseases, particularly due to the influence of thyroid hormone T3 on mood-regulating neurotransmitters like serotonin and noradrenalin.
  • Even after thyroid function is treated and normalized, mental health symptoms such as depression and anxiety can persist, indicating the complexity of these conditions.
  • It’s important to consider psychosocial factors like stress in treatment approaches for mental disorders related to Graves' disease, supporting the use of a bio-psycho-social model in therapy.

Article Abstract

Mental disorders merge highly with thyroid diseases. Because of its regulatory effects on serotonin and noradrenalin, T3 has been linked closely to depression and anxiety. It has known that in many cases, the mental symptoms persist even after normalization of thyroid function by treatment. Psychosocial factors including stress have been associated with mental symptoms even after thyroid function normalization in Graves' disease and a combination of mental disorders have been related to the exacerbation of hyperthyroidism. These findings suggest that psychosomatic approaches based on the bio-psycho-social medical model are important for the treatment of mental disorders associated with Graves' disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864135PMC
http://dx.doi.org/10.1016/j.jcte.2019.100207DOI Listing

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