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The use of adenosine to identify dormant conduction after accessory pathway ablation: a single center experience and literature review. | LitMetric

AI Article Synopsis

  • AVRT accounts for about 40% of supraventricular tachycardias, and after ablation, the recurrence rate is around 10%. Adenosine can help detect dormant conduction, potentially improving predictions about recurrence post-ablation.
  • A study of 65 patients who underwent AVRT ablation between 2011 and 2015 showed that only one patient (1.5%) had dormant conduction, resulting in a low overall recurrence rate of 4.6%.
  • The findings suggest that while adenosine can identify dormant conduction, its absence may not guarantee that the condition won’t recur; improved techniques, such as irrigated catheters and 3D mapping, may contribute to lower recurrence rates

Article Abstract

Introduction: Atrio-ventricular reentrant tachycardias (AVRT) represent around 40 percent of supraventricular tachycardias. After ablation, recurrence rates are around 10 percent. Adenosine has been described as a useful tool to assess presence of dormant conduction and predict recurrence after apparently successful ablation. We reviewed the patients of our service and assessed the role of adenosine in predicting dormant conduction and factors that could influence recurrence rates.

Methods: We retrospectively reviewed electrophysiologic studies and medical charts of 65 patients who had AVRT ablation and had adenosine used to assess dormant conduction at a single quaternary center between 2011 and 2015. Dormant conduction was defined as transient recovery of the preexcitation (for pathways with antegrade conduction) or return of the retrograde conduction through an apparently successfully ablated concealed accessory pathway (AP).

Results: One patient was found to have dormant conduction (1.5%) with early recurrence that was not further ablated due to the difficult location of the AP. The overall recurrence rate was 4.6%. General features like location of AP's, their properties, ablation times and technique were assessed.

Conclusion: Similar to its use in identifying other arrhythmias, adenosine may be useful in identifying dormant conduction for further ablation during initial ablation of an accessory pathway; however, the absence of dormant conduction on adenosine testing does not reliably predict non-recurrence. The low recurrence rates in our service may be related to the frequent use of irrigated tip catheters, 3D mapping and long average ablation time over the successful site of ablation.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872466PMC

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