Follicular hyperkeratotic spicules is a rare skin disorder that is usually associated with multiple myeloma. The condition typically presents with tiny hyperkeratotic spicules in follicular distribution and predominantly on the face. To our knowledge, there has been one reported case of this condition without underlying disease. We herein report the second case of idiopathic follicular hyperkeratotic spicules in a 54-year-old Thai woman presenting with multiple follicular horn-like spicules on her face and neck.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872986 | PMC |
| http://dx.doi.org/10.1159/000503272 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Generalized, Linear Hyperkeratotic Papules With Numerous White Spicules and Comedo-like Plugs.
JAMA Dermatol
February 2023
Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, China.
Trichodysplasia spinulosa polyomavirus small T antigen synergistically modulates S6 protein translation and DNA damage response pathways to shape host cell environment.
Virus Genes
February 2022
Department of Dermatology, McGovern Medical School at UT Health Science Center, 6431 Fannin Street, Houston, TX, 77030, USA.
TSPyV is a viral agent linked to Trichodysplasia spinulosa, a disfiguring human skin disease which presents with hyperkeratotic spicule eruption in immunocompromised hosts. This proliferative disease state requires extensive modulation of the host cell environment. While the small T (sT) antigen of TSPyV has been postulated to cause widespread cellular perturbation, its specific substrates and their mechanistic connection are unclear.
View Article and Find Full Text PDFFacial Spinulate Demodicosis.
Clin Cosmet Investig Dermatol
September 2021
Department of Internal Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Hyperkeratotic spicules are rare cutaneous lesions associated with underlying systemic illnesses. In more recent times, facial spinulate demodicosis has been suggested as an etiological factor. Demodicosis is a common dermatological condition characterized by the presence of Demodex mites in the pilocutaneous follicles.
View Article and Find Full Text PDFSpiky/keratosis-pilaris-like early follicular mycosis fungoides: A clinicopathologic study of 20 cases with extended follow-up.
J Cutan Pathol
September 2021
Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy.
Backgrounds: Follicular mycosis fungoides (FMFs) is a distinct form of T-cell lymphoma whose course is considered aggressive.
Methods: A retrospective study with long-term follow-up of 20 patients diagnosed with spiky/keratosis-pilaris-like FMF between 2008 and 2017 was conducted.
Results: Twelve males and eight females were identified, with a mean age at first diagnosis of 59 years (range 42-86).
A Case Report of Idiopathic Follicular Hyperkeratotic Spicules and Literature Review.
Case Rep Dermatol
October 2019
Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Follicular hyperkeratotic spicules is a rare skin disorder that is usually associated with multiple myeloma. The condition typically presents with tiny hyperkeratotic spicules in follicular distribution and predominantly on the face. To our knowledge, there has been one reported case of this condition without underlying disease.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!