Polymerization-driven successive collapse of DNA dominoes enabling highly sensitive cancer gene diagnosis.

Chem Commun (Camb)

Fujian Key Laboratory for Translational Research in Cancer and Neurodegenerative Diseases, Institute for Translational Medicine, Fujian Medical University, Fuzhou, Fujian 350108, China.

Published: December 2019

We propose a novel fluorescence assay method by designing a polymerization-driven DNA dominoes collapse (PDDC) strategy, enabling highly sensitive detection of p53 gene (as a model analyte) and single nucleotide polymorphism analysis.

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Source
http://dx.doi.org/10.1039/c9cc07508aDOI Listing

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