Amidst the recent bicentennial celebrations of the first publication, in 1818, of Mary Godwin Shelley's novel Frankenstein, little attention was given to the character Henry Clerval. Yet despite his few pages in the novel, Clerval's role as a humanist foil for Victor Frankenstein is significant. This brief coda examines what contemporary readers might learn from Clerval when his character is read allegorically, and how his presence in the novel makes clear that it can serve as a cautionary tale not only for biomedical scientists, but also for medical humanists.
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http://dx.doi.org/10.1353/pbm.2019.0041 | DOI Listing |
NPJ Antimicrob Resist
April 2024
Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, MOR, Mexico.
Salmonella enterica serovar Typhimurium ST213 is an emergent multidrug-resistant sequence type associated with the food chain, and gastrointestinal and invasive infections in North America. Here, we applied genomic and phenotypic analyses to illustrate the diversity and evolution of sequence type ST213. The population structure and evolutionary history of ST213 strains, particularly the North American isolates (NA-ST213) distinguish them from other S.
View Article and Find Full Text PDFPediatr Infect Dis J
January 2025
Department of Pediatrics, Sections of Hospital Medicine and Emergency Medicine, University of Colorado School of Medicine Aurora, Aurora, Colorado.
Am J Physiol Lung Cell Mol Physiol
January 2025
Dept. of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA.
Rigor and reproducibility are vital to scientific advancement. It is unclear whether a protocol optimized for tissue dissociation in one institution performs well universally. Here, we share our brand-new lab's experience with inter-institutional variability that led to the discovery that a protocol optimized for murine lung dissociation at Boston University (BU) fails to reproduce similar CD4 T cell, CD8 T cell, and B cell outcomes at the University of Michigan at Ann Arbor (U-M).
View Article and Find Full Text PDFMed J Malaysia
January 2025
Saveetha Institute of Medical and Technical Sciences, SIMATS Deemed University, Chennai, Tamilnadu, India.
Barotrauma is a medical condition caused by sudden pressure changes in the body causing damage to multiple parts of the body. However, it is an infrequent occurrence when it comes to Colo-rectal perforation, wherein the trauma occurs due to the insufflation of compressed air through the anus. Several factors influence the outcome of a patient with colonic perforation due to barotrauma such as the severity of the injury, hemodynamic status of the patient, the patient's general health and well-being, the time taken for active medical/ surgical intervention since the injury, aggressive intravenous antibiotics administration to prevent sepsis, post-operative complications like surgical site infection, post-op ileus, anastomotic leak, etc.
View Article and Find Full Text PDFKans J Med
September 2024
Department of Anesthesiology, University of Kansas School of Medicine-Wichita, Wichita, KS.
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