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Integrated metabolomics and network pharmacology reveal the procoagulant mechanisms of Cirsium setosum extracts.
J Chromatogr B Analyt Technol Biomed Life Sci
October 2024
Tianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China. Electronic address:
As a medicinal plant, Cirsium setosum has excellent procoagulant effects and has long been used as a cure for hemoptysis, epistaxis, uremia and metrorrhagia caused by blood heat. However, the key medicinal part of C. setosum, as well as the biologically active substances that play a major role, are not known.
View Article and Find Full Text PDFImpact of Simulation-based Mastery Learning on Management of Massive Hemoptysis.
ATS Sch
June 2024
Department of Medicine and.
Background: The management of massive hemoptysis is a high-risk, low-volume procedure that is associated with high mortality rates, and pulmonary and critical care medicine (PCCM) fellows often lack training. Simulation-based mastery learning (SBML) is an educational strategy that improves skill but has not been applied to massive hemoptysis management.
Objective: This pilot study aimed to develop a high-fidelity simulator, implement an SBML curriculum, and evaluate the impact on PCCM fellows managing massive hemoptysis.
A Prospective Study on Deep Inspiration Breath Hold Thoracic Radiation Therapy Guided by Bronchoscopically Implanted Electromagnetic Transponders.
Cancers (Basel)
April 2024
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA.
Background: Electromagnetic transponders bronchoscopically implanted near the tumor can be used to monitor deep inspiration breath hold (DIBH) for thoracic radiation therapy (RT). The feasibility and safety of this approach require further study.
Methods: We enrolled patients with primary lung cancer or lung metastases.
Caring for patients with life-threatening hemoptysis.
Nursing
February 2024
Leon Chen is a clinical program manager of Research and Simulated Learning in the Department of Anesthesiology & Critical Care Medicine at Memorial Sloan Kettering Cancer Center in New York, N.Y., and an associate professor of nursing at Columbia University School of Nursing in New York, N.Y. Brian Fasolka is a clinical associate professor at NYU Rory Meyers College of Nursing in New York, N.Y.
Life-threatening hemoptysis (formerly called massive hemoptysis), though relatively uncommon, imposes significant mortality risks. This article discusses the etiology, clinical presentation, assessment, treatment, and nursing interventions to promote effective clinical management of patients with this condition.
View Article and Find Full Text PDFA bench study on the prevention of lung-to-lung aspiration with double-lumen endobronchial tubes and bronchial blockers.
Sci Rep
January 2024
Department of Anesthesiology and Pain Medicine, SMG-SNU Boramae Medical Center, College of Medicine, Seoul National University, Boramaero 5-Gil, Dongjakgu, Seoul, 07061, Republic of Korea.
Effective lung isolation prevents lung-to-lung aspiration during thoracotomy for the management of hemoptysis. Double-lumen endobronchial tubes (DLT) and bronchial blockers are commonly used for lung separation during thoracic surgery. In this study, the fluid-sealing characteristics of the endobronchial cuffs of three different commercially available DLTs (Broncho-Cath with a polyvinylchloride cuff, Broncho-Cath with a polyurethane cuff, and Human Broncho with a silicone cuff) and two different bronchial blockers (Arndt and Coopdech bronchial blockers) were evaluated using a benchtop model.
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