AI Article Synopsis
- Funiculitis is an inflammation of the spermatic cord, mainly caused by bacterial infections from nearby structures, but it can also have non-infectious causes.
- A case study of a 72-year-old man showed that despite treatment with antibiotics, he developed systemic symptoms, leading to suspicion of a non-infectious cause, specifically medium vessel vasculitis.
- Diagnostic imaging (PET and CT angiography) helped identify the vasculitis, and the patient responded positively to corticosteroids, highlighting the importance of considering vasculitis in funiculitis cases that don't improve with antibiotics.
Article Abstract
: Funiculitis, an inflammation of the spermatic cord, usually results from infection of adjacent structures like the epididymis, testis or the urethra. It is most frequently caused by a bacterial infection, but has a broad (non-infectious) differential diagnosis.: This case illustrates an unusual cause of funiculitis. A 72-year old man presented with sequential right- and left side funiculitis. He was non-responsive to antibiotics and developed constitutional symptoms. A non-infectious inflammatory etiology was suspected and further diagnostic procedures were performed.: PET findings suggested medium and large vessel vasculitis. CT angiography and histopathological analysis of the spermatic cord lacked the typical characteristics of Polyarteritis Nodosa (PAN) or medium size vasculitis. In light of a probable medium vessel vasculitis the patient was treated with corticosteroids, with a favorable response.: Vasculitis should be considered in the differential diagnosis of a funiculitis that does not respond to antibiotic therapy. PET CT is an important tool for the diagnosis of vasculitis in patients with an atypical presentation and inconclusive diagnostic testing.
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| http://dx.doi.org/10.1080/17843286.2019.1696029 | DOI Listing |
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