The pathogenic power of Streptococcus pseudopneumoniae has been specified over years, particularly in case of chronic respiratory diseases; S. pseudopneumoniae isolation has however not been characterized before in CF patients. Identification of S. pseudopneumoniae remains challenging due to the high simila-rity level between species of the Streptococcus mitis group. Twenty CF patients with S. pseudopneumoniae were included. Isolates initially identified by phenotypic routine methods were subjected to both recA sequencing and amplification of S. pseudopneumoniae specific markers. Microbiological and clinical data were reviewed for patients with confirmed S. pseudopneumoniae. Thirteen isolates actually belong to S. pseudopneumoniae. S. pseudopneumoniae was associated with pulmonary exacerbation in 46% of the patients, either as the sole pathogen or as part of a polymicrobial infectious process. S. pseudopneumoniae has to be considered as an additional opportunistic pathogen in CF and additional studies are needed to increase knowledge of its epidemiology and clinical significance in CF.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jcf.2019.11.004 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Diagnostic and prognostic values of NSCLC patients with or without obstructive pneumonia after sleeve lobectomy.
Front Cell Infect Microbiol
December 2024
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Objective: We aimed to identify the diagnostic value of next-generation sequencing (NGS) of bronchoalveolar lavage fluid (BALF) from patients with non-small-cell lung cancer (NSCLC).
Methods: Forty patients who were initially diagnosed with pulmonary nodules were enrolled. Frozen section histology was used to identify the NSCLC cell types.
The pneumococcal bacteriocin streptococcin B is produced as part of the early competence cascade and promotes intraspecies competition.
mBio
December 2024
Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA.
Unlabelled: is an important human pathogen that normally resides in the human nasopharynx. Competence-mediated bacteriocin expression by plays a major role in both the establishment and persistence of colonization on this polymicrobial surface. Over 20 distinct bacteriocin loci have been identified in pneumococcal genomes, but only a small number have been characterized phenotypically.
View Article and Find Full Text PDFRespiratory pathogens carriage in guinea pigs raised as livestock in Ecuador: A proxy to study a neglected reservoir for zoonotic transmission in the Andean Region.
Acta Trop
January 2025
One Health Research Group. Universidad de Las Américas. Quito. Ecuador. Electronic address:
In the Andean region of South America, guinea pigs (Cavia porcellus) are raised as livestock in close contact with other domestic animals and humans. Although the susceptibility of guinea pigs to being affected by a wide range of diseases is well known as a laboratory animal model, there are a few reports about the potential role of zoonotic pathogens in livestock guinea pigs. In this work, we analyzed the nasopharyngeal carriage of respiratory pathogenic viruses and bacteria in guinea pigs from farms in Ecuador.
View Article and Find Full Text PDFA case of bacteremia by Streptococcus pseudopneumoniae.
Enferm Infecc Microbiol Clin (Engl Ed)
December 2024
Clinical Microbiology Unit, Public Health Regional Laboratory of the Community of Madrid, Directorate General of Public Health, Regional Ministry of Health of Madrid, Madrid, Spain; CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.
A novel LAMP-based assay for the identification of and in clinical isolates.
J Clin Microbiol
December 2024
Division of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
Article Synopsis
- * Identifying specific species within SMG is challenging due to their genetic similarities, making traditional testing methods (like phenotypic tests and MALDI-TOF) unreliable.
- * This study introduced a new method called LAMP (loop-mediated isothermal amplification) that uses unique molecular markers for accurate and quick identification of relevant SMG clinical isolates.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!