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Clinical feasibility study of transcatheter edge-to-edge mitral valve repair in dogs with the canine V-Clamp device.
Front Vet Sci
December 2024
Department of Clinical Sciences and James L. Voss Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.
Objective: To determine procedural feasibility, safety, and short-term efficacy in dogs with severe degenerative mitral regurgitation (MR) undergoing transcatheter edge-to-edge repair (TEER) with a canine-specific device.
Design: Prospective, single-arm (uncontrolled), single-institution clinical feasibility study.
Animals: Fifty client-owned dogs with severe degenerative MR operated over a 28-month period.
Article Synopsis
- - Mitral regurgitation (MR) is the second most common heart valve disease, and severe cases often require surgical intervention, though high-risk patients may need alternative treatments like transcatheter edge-to-edge valve repair or the Tendyne valve.
- - The Tendyne valve, which can be implanted without traditional surgery, showed promising results: 93.2% of patients had no MR after treatment, and heart failure hospitalizations significantly decreased post-surgery.
- - An economic analysis indicated that using the Tendyne valve is cost-effective compared to medications, with a favorable cost per quality-adjusted life year, and around 60 patients annually could benefit from this treatment in Poland.
Prevention of left ventricular outflow tract obstruction in transapical mitral valve replacement: the MitraCut procedure.
EuroIntervention
November 2024
Department of Cardiac Surgery, Medical University Pisa, Pisa, Italy.
Article Synopsis
- The MitraCut procedure is an innovative technique involving endoscopic scissors to cut the anterior mitral leaflet during transapical transcatheter mitral valve replacement (TA-TMVR) to prevent left ventricular outflow tract (LVOT) obstruction.
- In a study across six European centers, outcomes were reviewed for 13 high-risk patients who underwent this procedure, showing a high success rate with minimal complications.
- The findings suggest that the MitraCut procedure is effective at preventing LVOT obstruction, with no postoperative obstructions, a low rate of minor leaks, and no in-hospital or 30-day mortalities among the patients.
Management of giant left atrial thrombus late after transcatheter mitral valve-in-ring replacement using a transcatheter aortic valve: a case report.
BMC Cardiovasc Disord
November 2024
Department of Internal Medicine I, Cardiology, Angiology, Intensive Medical Care, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.
Background: In symptomatic high-risk patients with severe mitral valve regurgitation (MR), who are not eligible for surgery, Transcatheter edge-to-edge repair (TEER) or transcatheter mitral valve replacement (TMVR) may be an option, especially when surgical mitral valve repair by annuloplasty has been performed earlier. After TMVR, the appropriate anticoagulation regimen is still matter of debate.
Case Presentation: We here report on a 78-year-old frail lady with heart failure and atrial fibrillation who underwent surgical reconstruction of the mitral valve nine years ago.
Transcaval access for transcatheter aortic valve implantation: A meta-analysis and systematic review.
Int J Cardiol
January 2025
Department of Cardiology, Mayo Clinic, Phoenix, AZ, United States of America.
Background: Anatomical factors may preclude transfemoral (TF) arterial access for transcatheter aortic valve implantation (TAVI). Transcaval (TCav) access has been utilized as an alternative access for these patients. We aimed to investigate the outcomes of TCav access in patients undergoing TAVI.
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