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Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI. | LitMetric

AI Article Synopsis

  • The consensus process involved two surveys, with the first identifying 4 key consensus items for T1 mapping, and the second, covering both T1 and T2 mapping, reaching consensus on 32 out of 54 items.
  • Despite these recommendations, there remains significant disagreement on renal T1 and especially T2 mapping, indicating that more research is necessary to standardize protocols across different sites for better clinical use.

Article Abstract

To develop technical recommendations on the acquisition and post-processing of renal longitudinal (T1) and transverse (T2) relaxation time mapping. A multidisciplinary panel consisting of 18 experts in the field of renal T1 and T2 mapping participated in a consensus project, which was initiated by the European Cooperation in Science and Technology Action PARENCHIMA CA16103. Consensus recommendations were formulated using a two-step modified Delphi method. The first survey consisted of 56 items on T1 mapping, of which 4 reached the pre-defined consensus threshold of 75% or higher. The second survey was expanded to include both T1 and T2 mapping, and consisted of 54 items of which 32 reached consensus. Recommendations based were formulated on hardware, patient preparation, acquisition, analysis and reporting. Consensus-based technical recommendations for renal T1 and T2 mapping were formulated. However, there was considerable lack of consensus for renal T1 and particularly renal T2 mapping, to some extent surprising considering the long history of relaxometry in MRI, highlighting key knowledge gaps that require further work. This paper should be regarded as a first step in a long-term evidence-based iterative process towards ever increasing harmonization of scan protocols across sites, to ultimately facilitate clinical implementation.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021750PMC
http://dx.doi.org/10.1007/s10334-019-00797-5DOI Listing

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