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Therapeutic potential of Xihuang Pill in colorectal cancer: Metabolomic and microbiome-driven approaches.
Front Pharmacol
December 2024
Department of oncology, The Third Affiliated Hospital, Beijing University of Chinese Medicine, Beijing, China.
Introduction: The Xihuang Pill (XHP), a venerated traditional Chinese medicine, has demonstrated significant anti-cancer capabilities. Despite its proven efficacy, the scarcity of comprehensive pharmacological studies limits the widespread application of XHP. This research endeavor seeks to demystify the therapeutic underpinnings of XHP, particularly in the realm of colorectal cancer (CRC) therapy.
View Article and Find Full Text PDFMetastability demystified - the foundational past, the pragmatic present and the promising future.
Nat Rev Neurosci
December 2024
Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Healthy brain function depends on balancing stable integration between brain areas for effective coordinated functioning, with coexisting segregation that allows subsystems to express their functional specialization. Metastability, a concept from the dynamical systems literature, has been proposed as a key signature that characterizes this balance. Building on this principle, the neuroscience literature has leveraged the phenomenon of metastability to investigate various aspects of brain function in health and disease.
View Article and Find Full Text PDFVisual insights into translation: demystifying trends of adopting eye-tracking techniques in translation studies.
Front Psychol
November 2024
Beijing Foreign Studies University, Beijing, China.
Introduction: The increasing use of eye-tracking techniques in translation studies offers valuable insights into cognitive processes and behavioral strategies of translators, reflecting a significant trend within cognitive linguistics and translator training methodologies.
Methods: This review harnesses quantitative bibliometric analysis through Bibliometrix R-package with qualitative content assessment to evaluate the trajectory and thematic evolution of eye-tracking research in translation studies. Through a dataset from the Web of Science, 56 articles were analyzed, revealing distinct thematic dimensions and trend dynamics.
Demystifying Synergistic Multifunctional Electrocatalysis of N-Doped Graphene/WS Heterostructure with Single-Atom Catalysts for Water Splitting and Fuel Cells.
ACS Appl Mater Interfaces
November 2024
Molecular Simulation Laboratory, Department of Physics, Bharathiar University, Coimbatore, Tamil Nadu 641 046, India.
As the demand for sustainable energy continues to rise, electrocatalysis has become increasingly prominent in the advancement of clean energy technologies. By scrutinizing the material to function as a multifunctional catalyst, the effectiveness of energy conversion processes is significantly enhanced. This study focuses on harnessing graphene/WS van der Waals heterostructures for overall water splitting and fuel cell applications, using transition metals (TMs) from Sc-Zn as single-atom catalysts (SACs).
View Article and Find Full Text PDFUnconventional structural evolution of an oxide surface in water unveiled by in situ sum-frequency spectroscopy.
Nat Chem
October 2024
Physics Department, State Key Laboratory of Surface Physics, Key Laboratory of Micro and Nano Photonic Structures, Ministry of Education, Fudan University, Shanghai, China.
Article Synopsis
- - Oxide-water interfaces are crucial for various natural and industrial reactions, but understanding at a molecular level is limited due to challenges in studying these concealed surfaces.
- - Researchers developed a new method using in situ sum-frequency vibrational spectroscopy to investigate silica-water interactions, revealing unexpected reaction pathways.
- - The study uncovered a surface reconstruction caused by the deprotonation of hydroxyl groups, leading to unusual silicon structures, which changes the understanding of aqueous silica chemistry and opens avenues for studying other oxide-water interfaces.
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