Human pegivirus in brain tissue of a patient with encephalitis.

Diagn Microbiol Infect Dis

Nepean Hospital, PO Box 63, Penrith, NSW 2751, Australia. Electronic address:

Published: February 2020

We describe a case of meningoencephalitis in which meta-transcriptomic (RNA) sequencing detected human pegivirus (HPgV) in brain tissue, cerebrospinal fluid, and serum in the absence of other pathogens. This is the first detection of HPgV in antemortem brain tissue, although it is uncertain whether HPgV is responsible for the observed encephalitis.

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Source
http://dx.doi.org/10.1016/j.diagmicrobio.2019.114898DOI Listing

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