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Challenges and opportunities of vaccination during pregnancy: perspectives of 20 healthcare professionals.
J Public Health Policy
January 2025
George's School of Health and Medical Sciences, Population Health Research Institute, City St George's, University of London, London, UK.
Vaccination during pregnancy is crucial due to increased maternal vulnerability to infectious diseases. However, uptake of recommended vaccines (influenza, pertussis, COVID-19) remains suboptimal, particularly among disadvantaged groups. This qualitative study explored healthcare professionals' (HCPs) perspectives, selected purposively, on factors influencing maternal vaccination in London.
View Article and Find Full Text PDFIntroduction: Early pregnancy care involves the screening and identification of women with risk factors for adverse pregnancy outcomes, including stillbirth or preterm birth, to tailor pregnancy care and interventions accordingly. Most stillbirths and approximately two-thirds of preterm births, however, occur in the absence of evident risk factors. The majority of stillbirths occur in the preterm period, yet there are few interventions targeting this period, and progress to reduce stillbirth rates remains slow.
View Article and Find Full Text PDFPrevalence of vitamin D deficiency and its association with adverse obstetric outcomes among pregnant women in Uganda: a cross-sectional study.
BMJ Open
January 2025
Department of Obstetrics and Gynaecology, Uganda Martyrs University, Mother Kevin Postgraduate Medical School, Nsambya Campus, Kampala, Uganda.
Objective: There is a dearth of published data on the vitamin D status of the Ugandan population; the objective of the study was to determine the prevalence of vitamin D deficiency among pregnant women in Uganda and its associations with maternal characteristics and adverse foetal-maternal outcomes.
Study Design And Setting: We conducted a cross-sectional study on pregnant women admitted to a tertiary referral hospital in Kampala, Uganda for delivery during the study period from July to December 2023.
Participants: The study was conducted on 351 pregnant women aged ≥18 years who consented to participate in the study, who had a single intrauterine pregnancy and a gestational age greater than 26 weeks, and who delivered at St.
Changes in doxylamine-pyridoxine dispensation in Ontario following media attention: Time-series analysis.
Can Fam Physician
January 2025
Assistant Professor in the Leslie Dan Faculty of Pharmacy at the University of Toronto, Scientist at Women's College Hospital Institute for Health System Solutions and Virtual Care in Toronto, Investigator with the Ontario Drug Policy Research Network, and Adjunct Scientist at ICES.
Objective: To understand the possible association between media coverage and changes in the dispensation of doxylamine-pyridoxine in Canada.
Design: Cross-sectional time-series analysis using data from the IQVIA CompuScript database.
Setting: Ten Canadian provinces.
Which variables are associated with recruitment failure? A nationwide review on obstetrical and gynaecological multicentre RCTs (2003-2023).
BMJ Open
January 2025
Reproduction and Development Research Institute, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands
Objective: We aim to assess which variables are associated with recruitment failure of obstetrical and gynaecological randomised controlled trials (RCTs), leading to an extension of the study period.
Design: Nationwide study.
Setting: A cohort of RCTs supported by the trial centre of the Dutch Consortium of Obstetrics and Gynaecology.
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